ATP5C1

Gene Symbol	ATP5C1
Entrez Gene	509
Alt Symbol	ATP5C, ATP5CL1
Species	Human
Gene Type	protein-coding
Description	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
Other Description	ATP synthase gamma chain, mitochondrial|ATP synthase subunit gamma, mitochondrial|F-ATPase gamma subunit|mitochondrial ATP synthase, gamma subunit 1
Swissprots	Q6I9V2 Q5VYP3 P36542 A8KA31 Q96AS8
Accessions	BAA03994 BAA03995 EAW86372 EAW86373 P36542 AK292896 BAF85585 AK294061 BAG57407 AK296803 BAG59376 BC000470 AAH00470 BC000931 AAH00931 BC010380 BC013394 AAH13394 BC013865 BC016812 AAH16812 BC020824 AAH20824 BC026049 AAH26049 BQ893894 CR457403 CAG33684 D16562 BAA03996 D16563 BAA03997 HQ448142 ADQ32623 XM_011519490 XP_011517792 NM_001001973 NP_001001973 NM_005174 NP_005165
Function	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Subcellular Location	Mitochondrion. Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity	Isoform Heart is expressed specifically in the heart and skeletal muscle, which require rapid energy supply. Isoform Liver is expressed in the brain, liver and kidney. Isoform Heart and Isoform Liver are expressed in the skin, intestine, stomach and aorta.
Top Pathways	Alzheimer's disease, Huntington's disease, Oxidative phosphorylation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ATPG full length protein - ab152210 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human ATPG full length protein - ab156752 from Abcam Category Protein Prices $297.00 Sizes 100 µg Source E. coli Species Human

ATP5C1 Antibody Blocking Peptide - LS-E10020 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ATPG Recombinant Protein - H00000509-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human ATPG Protein - NBP2-22699 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

ATP5C1-Antibody-N-term-Blocking-Peptide - BP9239a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human ATP5C1 protein - orb191192 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli Species Human

ATP5C1 protein (His tag) - 80R-2842 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

ATP synthase subunit gamma (26-298, His-tag) - AR50961PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

ATP synthase subunit gamma (26-298, His-tag) - AR50961PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

ATP synthase subunit gamma - H00000509-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ATP synthase subunit gamma - H00000509-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ATP5C1, 26-298aa, Human, His tag, E.coli - 01-P2137 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

ATP5C1 fusion protein - Ag1343 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human ATP5C1, His-tagged - ATP5C1-7626H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human ATP5C1, GST-tagged - ATP5C1-10016H from Creative Biomart Category Protein Source E.coli Species Human

ATP5C1 (D165) Peptide - BS3080P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human ATP synthase subunit gamma, mitochondrial(ATP5C1) - CSB-YP002353HU CSB-EP002353HU CSB-BP002353HU CSB-MP002353HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ATP5C1, 26-298aa, Human, His tag, E.coli (Denatured) - ATGP2137 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

ATP synthase subunit gamma (full length, N-term HIS tag, transcript variant 2) - TP760368 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

ATP synthase subunit gamma (full length, N-term HIS tag, transcript variant 1) - TP760511 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

ATP Synthase Gamma Chain, Recombinant Protein - MBS146332 from MyBioSource Category Protein Prices $140.00, $205.00, $2,665.00 Sizes 5 µg, 20 µg, 1 mg Source E Coli

ATP synthase subunit gamma, mitochondrial (ATP5C1) , Recombinant Protein - MBS1326278 from MyBioSource Category Protein Prices $1,585.00, $1,585.00, $2,045.00, $2,045.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Orangutan

ATP synthase subunit gamma, mitochondrial (ATP5C1) , Recombinant Protein - MBS958676 from MyBioSource Category Protein Prices $1,585.00, $1,585.00, $2,050.00, $2,050.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ATP5C1, Recombinant Protein - MBS205020 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 100 µg, 500 µg Source E Coli Species Human

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