AADAT

Gene Symbol AADAT
Entrez Gene 51166
Alt Symbol KAT2, KATII
Species Human
Gene Type protein-coding
Description aminoadipate aminotransferase
Other Description 2-aminoadipate aminotransferase|2-aminoadipate transaminase|KAT/AadAT|L kynurenine/alpha aminoadipate aminotransferase|alpha-aminoadipate aminotransferase|kynurenine aminotransferase II|kynurenine--oxoglutarate aminotransferase II|kynurenine--oxoglutarate transaminase 2|kynurenine--oxoglutarate transaminase II|kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Swissprots Q9UL02 B3KP84 Q8N5Z0
Accessions AAY41030 EAX04770 EAX04771 EAX04772 Q8N5Z0 AF481738 AAM09683 AI190763 AK055952 BAG51596 AK314729 BAG37271 BC031068 AAH31068 HQ447955 ADQ32439 XM_006714231 XP_006714294 XM_011532020 XP_011530322 NM_001286682 NP_001273611 NM_001286683 NP_001273612 NM_016228 NP_057312 NM_182662 NP_872603
Function Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). {ECO:0000269|PubMed:18620547}.
Subcellular Location Mitochondrion {ECO:0000305}.
Tissue Specificity Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary.
Top Pathways Lysine degradation, Tryptophan metabolism, Lysine biosynthesis, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism

AADAT-Over-expression-Lysate - LY14137a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag AADAT (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AADAT gene.

AADAT 293T Cell Transient Overexpression Lysate(Denatured) - H00051166-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

AADAT 293 Cell Lysate - 406779 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

alpha-Aminoadipate Aminotransferase Overexpression Lysate (Denatured) - H00051166-T01 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl
Species Human
Western Blot: AADAT Overexpression Lysate [H00051166-T01] - Lane 1: AADAT transfected lysate (47.3 KDa) Lane 2: Non-transfected lysate.

alpha-Aminoadipate Aminotransferase Overexpression Lysate (Native) - NBL1-07164 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: AADAT Overexpression Lysate (Adult Normal) [NBL1-07164] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for AADAT.

AADAT Over-expression Lysate Product - GWB-4F731D from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

alpha-Aminoadipate Aminotransferase Overexpression Lysate (Native) - NBP2-04829 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: AADAT Overexpression Lysate (Adult Normal) [NBP2-04829] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for AADAT.

Panoply™ Human AADAT Knockdown Stable Cell Line - CSC-DC000012 from Creative biogene

Category Cell Line
Species Human

Human AADAT Knockout Cell Line-HEK293T - CSC-RT1224 from Creative biogene

Category Cell Line
Species Human

AADAT KO Cell Lysate-HEK293T - CLKO-1077 from Creative biogene

Category Cell Lysate
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