Tnf

Gene Symbol	Tnf
Entrez Gene	24835
Alt Symbol	RATTNF, TNF-alpha, Tnfa
Species	Rat
Gene Type	protein-coding
Description	tumor necrosis factor
Other Description	cachectin|tumor necrosis factor (TNF superfamily, member 2)|tumor necrosis factor alpha|tumor necrosis factor ligand superfamily member 2
Swissprots	Q6EE11 Q9JI27 P16599 Q9JI26
Accessions	AAA16275 AAA42255 AAK53568 AAK53569 AAK53570 AAK53571 AAK53572 AAK53573 AAR91624 AAR91625 AAR91626 BAA00367 CAE84003 EDL83547 EDL83548 P16599 AF269159 AAF82567 AF269160 AAF82568 AJ002278 CAA05290 BC107671 AAI07672 X66539 CAA47146 NM_012675 NP_036807
Function	Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
Subcellular Location	C-domain 2: Secreted {ECO:0000250}.
Top Pathways	Rheumatoid arthritis, Inflammatory bowel disease (IBD), Sphingolipid signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Cytokine-cytokine receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Recombinant Rat TNF-alpha Protein - NBP2-35300 from Novus Biologicals Category Protein Prices $69.00, $169.00, $2,669.00 Sizes 5 µg, 20 µg, 1 mg Source E. coli Species Rat

TNF-alpha Recombinant Protein - P4852 from Novus Biologicals Category Protein Prices $549.00 Sizes 20 µg Species Rat

TNF-alpha Protein - NBP1-99203 from Novus Biologicals Category Protein Species Rat

TNF-alpha Protein - NBP1-99616 from Novus Biologicals Category Protein Prices $469.00 Sizes 50 µg Species Rat

TNF alpha Recombinant Protein (Active) - GTX48271-PRO from GeneTex Category Protein Prices $299.00 Sizes 20 μg Source E. coli Species Rat

TNF alpha recombinant protein - GTX65409 from GeneTex Category Protein Prices $219.00 Sizes 10 μg Source E. coli Species Rat

TNF alpha recombinant protein - GTX65408 from GeneTex Category Protein Prices $359.00 Sizes 50 μg Source E. coli Species Rat

Recombinant Rat TNF-alpha - 510-RT-010 from R&D Systems Category Protein Source E. coli-derived, Leu80-Leu235, with an N-terminal Met

Recombinant Rat TNF-alpha - 510-RT-050 from R&D Systems Category Protein Source E. coli-derived, Leu80-Leu235, with an N-terminal Met

Recombinant Rat TNF-alpha, CF - 510-RT-010/CF from R&D Systems Category Protein Source E. coli-derived, Leu80-Leu235, with an N-terminal Met

Recombinant Rat TNF-alpha, CF - 510-RT-050/CF from R&D Systems Category Protein Source E. coli-derived, Leu80-Leu235, with an N-terminal Met

TNF a Protein (OPPA00654) - OPPA00654 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Rat TNF ALPHA Protein (OPSA11151) - OPSA11151 from Aviva Systems Biology Category Protein Prices $430.00 Sizes 20 µg Species Rat

Rat TNF alpha protein - orb84526 from Biorbyt Category Protein Prices $196.00, $323.00, $731.00, $2,278.00, $3,732.00 Sizes 5 μg, 20 μg, 100 μg, 500 μg, 1 mg Source E. coli Species Rat

TNF protein - 80R-4266 from Fitzgerald Category Protein Prices $295.00 Sizes 100 µg Source E.coli

Rat TNFa Protein - abx069529 from Abbexa Category Protein Source E.coli Species Rat

Tumor necrosis factor (TNF-alpha) (80-235, His-tag) - AR51948PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Rat

Tumor necrosis factor (TNF-alpha) (80-235, His-tag) - AR51948PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Rat

Tumor necrosis factor (TNF-alpha) - PA045 from Acris Antibodies Category Protein Prices $135.00 Sizes 5 µg Source E. coli Species Rat

Tumor necrosis factor (TNF-alpha) - PA045X from Acris Antibodies Category Protein Prices $235.00 Sizes 20 µg Source E. coli Species Rat

Tumor necrosis factor (TNF-alpha) - P4852 from Acris Antibodies Category Protein Prices $370.00 Sizes 20 µg Species Rat

Tumor necrosis factor (TNF-alpha) - P6043 from Acris Antibodies Category Protein Prices $370.00 Sizes 20 µg Species Rat

Tumor Necrosis Factor-Alpha, Rat Recombinant - 228-11520-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Rat

Recombinant Rat TNF-alpha - 228-11520-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Rat

Recombinant Rat TNF-alpha - 228-11520-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Rat

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