ABCE1

Gene Symbol ABCE1
Entrez Gene 6059
Alt Symbol ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family E (OABP), member 1
Other Description 2'-5'-oligoadenylate-binding protein|ATP-binding cassette sub-family E member 1|RNase L inhibitor|huHP68|ribonuclease 4 inhibitor|ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor
Swissprots Q6NR76 P61221
Accessions AAZ38723 EAX05049 P61221 AB062293 BAB93476 AK123593 AK315198 BC016283 AAH16283 BC016988 AAH16988 BT009779 AAP88781 DA218189 X74987 CAA52920 X76388 CAA53972 NM_001040876 NP_001035809 NM_002940 NP_002931
Function Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly. {ECO:0000269|PubMed:11585831, ECO:0000269|PubMed:9660177, ECO:0000269|PubMed:9847332}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11585831}. Mitochondrion {ECO:0000269|PubMed:11585831}. Note=Localized to clusters of virus formation at the plasma membrane.

ABCE1 (N-12) - sc-49338 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ABCE1 (N-12): sc-49338. Western blot analysis of ABCE1 expression in non-transfected: sc-117752 (A) and mouse ABCE1 transfected: sc-118158 (B) 293T whole cell lysates.

ABCE1 (H-105) - sc-99064 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ABCE1 (L-19) - sc-49337 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ABCE1 (L-19): sc-49337. Immunoperoxidase staining of formalin fixed, paraffin-embedded human upper stomach tissue showing cytoplasmic staining of glandular cells.

Anti-ABCE1 antibody - ab117997 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ABCE1 antibody (ab117997) at 1/2000 dilution + Hela cells at 65 µgdeveloped using the ECL technique

Anti-ABCE1 antibody - ab123727 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ABCE1 antibody (ab123727) at 1/100 dilution + A549 cell line lysates at 35 µg

Anti-ABCE1 antibody [EPR15373(B)] - C-terminal - ab185548 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15373(B)
All lanes : Anti-ABCE1 antibody [EPR15373(B)] - C-terminal (ab185548) at 1/5000 dilutionLane 1 : 293 cell lysateLane 2 : K562 cell lysateLane 3 : HeLa cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-ABCE1 Antibody (aa566-595, AP) - LS-C232313 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCE1 Antibody (aa566-595, FITC) - LS-C232315 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCE1 Antibody (aa566-595, PE) - LS-C232316 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCE1 Antibody (aa566-595) - LS-C319244 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCE1 Antibody (aa12-25) - LS-C87323 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ABCE1 Antibody (aa1-119, Biotin) - LS-C142157 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCE1 Antibody - LS-C137429 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCE1 Antibody (aa1-119) - LS-C2755 from LifeSpan Bioscience

Prices $335.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal
Human ABCE1 detected in immunoprecipitated samples using LS-C2755. Lane 1: HeLa cell lysates, Lane 2: HEK 293 cell lysates.

Anti-ABCE1 Antibody (aa579-590) - LS-C54433 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.3 ug/ml) staining of A431 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-ABCE1 Antibody (aa1-119, DY650) - LS-C142158 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCE1 Antibody (C-Terminus) - LS-C80599 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-ABCE1 Antibody (aa1-119, HRP) - LS-C142160 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCE1 Antibody (aa1-119, DY488) - LS-C142159 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCE1 Antibody (aa1-119, DY550) - LS-C142161 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCE1 Antibody (aa566-595, APC) - LS-C232312 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

ABCE1 Antibody - NB400-116 from Novus Biologicals

Prices $99.00, $299.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ABCE1 Antibody [NB400-116] - WB analysis of ABCE1 in A431 lysate.

ABCE1 Antibody - NBP2-15225 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ABCE1 Antibody [NBP2-15225] - 30 ug K562 whole cell lysate/extract, 7.5% SDS-PAGE gel, dilution 1:500.

ABCE1 Antibody - NB100-94888 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

ABCE1 Antibody [FITC] - NB400-116F from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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