SMC4

Gene Symbol SMC4
Entrez Gene 850775
Alt Symbol -
Species Yeast
Gene Type protein-coding
Description condensin subunit SMC4
Other Description -
Swissprots Q12267 D6VY86
Accessions DAA09402 Q12267 NM_001181973 NP_013187
Function Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Subcellular Location Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, condensin associates with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Top Pathways Cell cycle - yeast

Recombinant Saccharomyces cerevisiae Structural maintenance of chromosomes prot - CSB-YP623598SVG CSB-EP623598SVG CSB-BP623598SVG CSB-MP623598SVG from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Yeast

Structural maintenance of chromosomes protein 4 (SMC4), partial, Recombinant Protein - MBS1421209 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Yeast
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