INMT

Gene Symbol	INMT
Entrez Gene	11185
Alt Symbol	TEMT
Species	Human
Gene Type	protein-coding
Description	indolethylamine N-methyltransferase
Other Description	amine N-methyltransferase|aromatic alkylamine N-methyltransferase|arylamine N-methyltransferase|indolamine N-methyltransferase|nicotine N-methyltransferase|thioether S-methyltransferase
Swissprots	B8ZZ69 Q9UBY4 Q9UHQ0 Q3KP49 Q9P1Y2 O95050
Accessions	AAD04723 AAF18306 BAA94451 EAL24447 O95050 AF128846 AAF18304 AF128847 AAF18305 AK309519 AK313832 BC033813 AAH33813 BC103712 AAI03713 BC106902 AAI06903 BC106903 AAI06904 DA920005 NM_001199219 NP_001186148 NM_006774 NP_006765
Function	Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2- methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds (By similarity). Catalyzes the N-methylation of tryptamine and structurally related compounds. {ECO:0000250, ECO:0000269|PubMed:10552930}.
Subcellular Location	Cytoplasm {ECO:0000250}.
Tissue Specificity	Widely expressed. The highest levels were in thyroid, adrenal gland, adult and fetal lung. Intermediate levels in heart, placenta, skeletal muscle, testis, small intestine, pancreas, stomach, spinal cord, lymph node and trachea. Very low levels in adult and fetal kidney and liver, in adult spleen, thymus, ovary, colon and bone marrow. Not expressed in peripheral blood leukocytes and brain. {ECO:0000269|PubMed:10552930}.
Top Pathways	Selenocompound metabolism, Tryptophan metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

INMT (C-15) - sc-243083 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

INMT (N-13) - sc-243081 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-INMT antibody - ab174890 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-INMT antibody - ab84619 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-INMT antibody [EPR13240] - ab181854 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR13240

Anti-INMT antibody [EPR13240-105] - ab184573 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR13240-105

Anti-INMT Antibody (aa101-128, AP) - LS-C236625 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-INMT Antibody (aa101-128, APC) - LS-C246785 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-INMT Antibody (aa101-128, Biotin) - LS-C246786 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-INMT Antibody (aa101-128, FITC) - LS-C246787 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-INMT Antibody (aa101-128, PE) - LS-C246788 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-INMT Antibody (aa101-128, Azide-free, HRP) - LS-C249278 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-INMT Antibody - LS-C285541 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-INMT Antibody (HRP) - LS-C317416 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-INMT Antibody (FITC) - LS-C317418 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-INMT Antibody (aa108-137) - LS-C322247 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-INMT Antibody (Biotin) - LS-C317417 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-INMT Antibody (N-Terminus) - LS-C102317 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-INMT Antibody (aa101-128) - LS-C165243 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-INMT Antibody (aa63-223) - LS-C178532 from LifeSpan Bioscience Prices $255.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

INMT Antibody - NBP2-16967 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

INMT Antibody - NBP1-55015 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

INMT Antibody - H00011185-A01 from Novus Biologicals Prices $269.00 Sizes 50 µl Host Mouse Clonality Polyclonal

ANTI-INMT (CENTER) antibody produced in rabbit - SAB1303564 from Sigma-Aldrich Prices $326.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-INMT antibody produced in rabbit - HPA055180 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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