FGFR2

Gene Symbol FGFR2
Entrez Gene 2263
Alt Symbol BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
Species Human
Gene Type protein-coding
Description fibroblast growth factor receptor 2
Other Description BEK fibroblast growth factor receptor|FGF receptor|FGFR2-AHCYL1 fusion kinase protein|bacteria-expressed kinase|hydroxyaryl-protein kinase|keratinocyte growth factor receptor|protein tyrosine kinase, receptor like 14|soluble FGFR4 variant 4
Swissprots Q12922 Q9UNS7 Q1KHY5 Q9NZU3 Q14305 Q14718 Q9UQH8 Q9NZU2 Q9UIH4 Q14719 Q96KM0 Q8IXC7 Q9UD01 E9PCR0 Q86YI4 Q9UMC6 Q9UIH8 Q9UM87 Q96KM1 Q9UIH7 Q96KL9 Q9UIH3 Q9UQI0 Q9UQH9 P18443 Q14302 Q9UIH5 Q9UQH7 Q9UIH6 Q14301 Q14304 Q14303 Q14672 Q9UD02 Q96KM2 P21802 Q14300 Q01742 B4DFC2 E7EVR6
Accessions AAB19319 AAB19320 AAC41933 AAC41934 AAC41935 AAC41936 AAC41937 AAC41938 AAD14392 AAD31560 AAD31561 AAD31562 AAD31563 AAD31565 AAD31566 AAD31567 AAF43273 AAF43274 AAK94205 AAK94206 AAK94207 AAK94208 AAK94209 AAM74056 ABE96832 CAA76643 CAJ33699 CCQ43115 CCQ43116 EAW49338 EAW49339 EAW49340 EAW49341 EAW49342 EAW49343 EAW49344 EAW49345 EAW49346 EAW49347 EAW49348 EAW49349 EAW49350 EAW49351 EAW49352 EAW49353 EAW49354 EAW49355 EAW49356 EAW49357 EAW49358 EAW49359 EAW49360 P21802 AB030073 BAA89296 AB030074 BAA89297 AB030075 BAA89298 AB030076 BAA89299 AB030077 BAA89300 AB030078 BAA89301 AB084153 BAC45037 AB821309 BAO19692 AK026508 AK294026 BAG57383 AK308621 BC037338 BC039243 AAH39243 BC096749 CB305736 CN345547 CX873387 EF057068 ABO25744 EU826598 ACF47634 EU826599 ACF47635 EU826600 ACF47636 EU826601 ACF47637 HM437239 ADN43070 M55614 AAA61188 M80634 AAA36147 M87770 AAA59470 M87771 AAA59471 M87772 AAA59472 M97193 AAA52449 S41878 AAB19323 U11814 AAA68514 X52832 CAA37014 X56191 CAA39654 Z71929 CAA96492 XM_006717708 XP_006717771 XM_006717709 XP_006717772 XM_006717710 XP_006717773 XM_006717711 XP_006717774 XM_006717712 XP_006717775 XM_006717713 XP_006717776 XM_011539510 XP_011537812 NM_000141 NP_000132 NM_001144913 NP_001138385 NM_001144914 NP_001138386 NM_001144915 NP_001138387 NM_001144916 NP_001138388 NM_001144917 NP_001138389 NM_001144918 NP_001138390 NM_001144919 NP_001138391 NM_022970 NP_075259 NM_023029 NP_075418 NR_073009 NM_022971 NM_022972 NM_022973 NM_022974 NM_022975 NM_022976 NM_023028 NM_023030
Function Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in keratinocytes and immature osteoblasts, but promotes apoptosis in differentiated osteoblasts. Phosphorylates PLCG1, FRS2 and PAK4. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activatio
Subcellular Location Isoform 19: Secreted.
Top Pathways Rap1 signaling pathway, Central carbon metabolism in cancer, Signaling pathways regulating pluripotency of stem cells, PI3K-Akt signaling pathway, Endocytosis

PathScan ® Phospho-FGFR2 (panTyr) Sandwich ELISA Kit - 7954 from Cell Signaling Technology

Category ELISA Kit
Prices $489.00
Sizes 1 kit (96 assays)
Figure 1. Constitutive phosphorylation of FGFR2 in KATO III cells lysed in the presence of phosphatase inhibitors* (phospho lysate) is detected by PathScan ® Phospho-FGFR2 (panTyr) Sandwich ELISA Kit #7954 (upper, right). In contrast, a low level of phospho-FGFR2 protein is detected in KATO III cells lysed in the absence of phosphatase inhibitors (nonphospho lysate). Similar levels of total FGFR2 protein from both nonphospho and phospho lysates are detected by PathScan ® Total FGFR2 Sandwich ELISA Kit #7939 (upper, left). Absorbance at 450 nm is shown in the top figure while corresponding western blots using Phospho-FGF Receptor (Tyr653/654) Antibody #3471 (right) or a total FGFR2 Rabbit mAb (left) are shown in the bottom figure. *Phosphatase inhibitors include sodium pyrophosphate, β-glycerophosphate, and Na 3 VO 4 .

PathScan ® Total FGFR2 Sandwich ELISA Kit - 7939 from Cell Signaling Technology

Category ELISA Kit
Prices $489.00
Sizes 1 kit (96 assays)
Figure 1. Constitutive phosphorylation of FGFR2 in KATO III cells lysed in the presence of phosphatase inhibitors* (phospho lysate) is detected by PathScan ® Phospho-FGFR2 (panTyr) Sandwich ELISA Kit #7954 (upper, right). In contrast, a low level of phospho-FGFR2 protein is detected in KATO III cells lysed in the absence of phosphatase inhibitors (nonphospho lysate). Similar levels of total FGFR2 protein from both nonphospho and phospho lysates are detected by PathScan ® Total FGFR2 Sandwich ELISA Kit #7939 (upper, left). Absorbance at 450 nm is shown in the top figure while corresponding western blots using Phospho-FGF Receptor (Tyr653/654) Antibody #3471 (right) or a total FGFR2 Rabbit mAb (left) are shown in the bottom figure. *Phosphatase inhibitors include sodium pyrophosphate, β-glycerophosphate, and Na 3 VO 4 .

Human FGFR2 / FGF Receptor 2 ELISA Kit (Sandwich ELISA) - LS-F6521 from LifeSpan Bioscience

Category ELISA Kit
Prices $690.00
Sizes 1 plate
Sensitivity 12.2 pg/ml
Range 31.25-2000 pg/ml

Mouse/Human/Rat FGFR2 / FGF Receptor 2 ELISA Kit (Cell-Based ELISA) - LS-F1989 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate
Range 31.25-2000 pg/ml

Phosphotyrosine FGFR2 / Fibroblast Growth Factor Receptor 2 ELISA Kit - RAB0962 from Sigma-Aldrich

Category ELISA Kit
Prices $637.00
Sizes 1 kt

Phospho-FGF R2 alpha DuoSet IC ELISA - DYC684-2 from R&D Systems

Category ELISA Kit
Prices $329.00, $649.00, $1,425.00
Sizes 1 kit (for 2 Plates), 1 kit (for 5 Plates), 1 pack (for 15 Plates)

Phospho-FGF R2 alpha DuoSet IC, 5 Plate - DYC684-5 from R&D Systems

Category ELISA Kit

Human Total FGF R2 alpha DuoSet IC ELISA - DYC665-2 from R&D Systems

Category ELISA Kit
Prices $329.00, $649.00
Sizes 1 kit (for 2 Plates), 1 kit (for 5 Plates)
Range 156.00 - 10,000 pg/mL

Human Total FGF R2 alpha DuoSet IC, 5 Plate - DYC665-5 from R&D Systems

Category ELISA Kit

Human FGFR2 ELISA kit - orb232178 from Biorbyt

Category ELISA Kit
Prices $604.00
Sizes 1 kit

Human FGFR2 ELISA Kit - abx151531 from Abbexa

Category ELISA Kit
Sensitivity 12.2 pg/ml
Range 31.25 pg/ml - 2000 pg/ml

Fibroblast Growth Factor Receptor 2, FGFR2, Human, ELISA Kit - E-EL-H0158 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 18.75
Range 31.25-2000pg/mL

Fibroblast growth factor receptor 2 (FGFR2), Human, ELISA Kit - CSB-EL008645HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 1.95 pg/ml
Range 7.8 pg/ml-500 pg/ml

Fibroblast Growth Factor Receptor 2 (FGFR2), Human, ELISA Kit - SEB794Hu from ARP American Research Products

Category ELISA Kit
Prices $685.00
Sizes 96 t
Sensitivity 12.2pg/mL
Range 31.2-2,000pg/mL

Fibroblast Growth Factor Receptor 2, FGFR2, Rabbit, ELISA Kit - E-EL-RB0162 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Fibroblast Growth Factor Receptor 2, FGFR2, Chicken, ELISA Kit - E-EL-Ch1400 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Fibroblast Growth Factor Receptor 2, FGFR2, Porcine, ELISA Kit - E-EL-P0562 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Fibroblast Growth Factor Receptor 2, FGFR2, Sheep, ELISA Kit - E-EL-S0334 from ARP American Research Products

Category ELISA Kit
Prices $648.00
Sizes 96 t

Fibroblast Growth Factor Receptor 2, FGFR2, Guinea Pig, ELISA Kit - E-EL-GP0283 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Fibroblast Growth Factor Receptor 2, FGFR2, Monkey, ELISA Kit - E-EL-MK0270 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Human KGFR ELISA Kit - HK0031 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Anserine KGFR ELISA Kit - AK0031 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

FGFR2 Colorimetric Cell-Based ELISA Kit - CB5264 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

Human FGFR2(Fibroblast Growth Factor Receptor 2) ELISA Kit - E-EL-H0158 from Elabscience

Category ELISA Kit
Sensitivity 18.75 pg/mL
Range 31.25—2000 pg/mL
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