ERCC3

Gene Symbol ERCC3
Entrez Gene 2071
Alt Symbol BTF2, GTF2H, RAD25, TFIIH, XPB
Species Human
Gene Type protein-coding
Description excision repair cross-complementation group 3
Other Description BTF2 p89|DNA excision repair protein ERCC-3|DNA repair helicase|DNA repair protein complementing XP-B cells|TFIIH 89 kDa subunit|TFIIH basal transcription factor complex 89 kDa subunit|TFIIH basal transcription factor complex helicase XPB subunit|TFIIH p89|basic transcription factor 2 89 kDa subunit|excision repair cross-complementing rodent repair deficiency, complementation group 3|xeroderma pigmentosum group B-complementing protein|xeroderma pigmentosum, complementation group B
Swissprots Q53QM0 P19447
Accessions AAN46739 AAY15069 EAW95311 EAW95312 EAW95313 EAW95314 P19447 AI222871 AK091500 BAG52374 AK095557 BAG53083 AK126697 AK127469 AK222465 BAD96185 AK290474 BAF83163 AK300250 BAG62016 AK307338 AK309405 BC008820 AAH08820 DQ893802 ABM84728 EU176179 ABW03630 M31899 AAA52396 XM_011510794 XP_011509096 XM_011510795 XP_011509097 NM_000122 NP_000113 NM_001303416 NP_001290345 NM_001303418 NP_001290347
Function ATP-dependent 3'-5' DNA helicase, component of the core- TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage. {ECO:0000269|PubMed:10024882, ECO:0000269|PubMed:8157004}.
Subcellular Location Nucleus.
Top Pathways Nucleotide excision repair, Basal transcription factors

TFIIH p89 CRISPR/Cas9 KO Plasmid (h) - sc-401124 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFIIH p89 HDR Plasmid (h) - sc-401124-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFIIH p89 Double Nickase Plasmid (h) - sc-401124-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFIIH p89 Double Nickase Plasmid (h2) - sc-401124-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFIIH p89 CRISPR Activation Plasmid (h) - sc-401124-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFIIH p89 CRISPR Activation Plasmid (h2) - sc-401124-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFIIH p89 Lentiviral Activation Particles (h) - sc-401124-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFIIH p89 Lentiviral Activation Particles (h2) - sc-401124-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFIIH p89 siRNA (h) - sc-36655 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TFIIH p89 shRNA Plasmid (h) - sc-36655-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TFIIH p89 shRNA (h) Lentiviral Particles - sc-36655-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XPB RNAi - H00002071-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU040001 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7950 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7950 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02034 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02034

ERCC3 siRNA (Human) - CRH1446 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ERCC3 - MBS8227782 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ERCC3 (NM_000122.1) - SHH286901 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ERCC3(NM_000122.1) - SHH038189 from Creative biogene

Category siRNA
Species Reactivities Human

Human ERCC3 siRNA - orb261948 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ERCC3 shRNA Plasmid (Human) - CHH1446 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ERCC3 miRNA 3'UTR clone - MiUTR1H-03289 from Creative biogene

Species Reactivities Human
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