| Gene Symbol |
ALDH4A1
|
| Entrez Gene |
100126042
|
| Alt Symbol |
-
|
| Species |
Bovine
|
| Gene Type |
protein-coding
|
| Description |
aldehyde dehydrogenase 4 family, member A1
|
| Other Description |
L-glutamate gamma-semialdehyde dehydrogenase|P5C dehydrogenase|aldehyde dehydrogenase family 4 member A1|delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
|
| Swissprots |
A7YWE4
|
| Accessions |
A7YWE4 DAA32054 BC134524 AAI34525 NM_001105646 NP_001099116
|
| Function |
Irreversible conversion of delta-1-pyrroline-5- carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion matrix {ECO:0000250}.
|
| Top Pathways |
Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
|