WTAP

Gene Symbol	WTAP
Entrez Gene	9589
Alt Symbol	Mum2
Species	Human
Gene Type	protein-coding
Description	Wilms tumor 1 associated protein
Other Description	PNAS-132|WT1-associated protein|Wilms' tumour 1-associating protein|female-lethal(2)D homolog|hFL(2)D|pre-mRNA-splicing regulator WTAP|putative pre-mRNA splicing regulator female-lethal(2D)|wilms tumor 1-associating protein
Swissprots	Q9BYJ7 Q15007 Q5TCL9 Q9H4E2 Q96T28 Q5TCL8
Accessions	EAW47622 EAW47623 EAW47624 EAW47625 EAW47626 EAW47627 EAW47628 Q15007 AA706250 AF277190 AAK07548 AF374416 AAK54764 AJ276706 CAC10188 AK127822 BAG54579 AK131393 AK290854 BAF83543 AL583911 CAC29495 BC000383 AAH00383 BC004432 AAH04432 BC028180 BC069192 AAH69192 BE906617 BG702882 BQ778248 BQ948913 BX387163 CN284477 CR627456 CAH10537 D14661 BAA03495 DA138013 DA561768 HQ447554 ADQ32040 XM_011536264 XP_011534566 NM_001270531 NP_001257460 NM_001270532 NP_001257461 NM_001270533 NP_001257462 NM_004906 NP_004897 NM_152857 NP_690596 NM_152858 NP_690597
Function	Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes. {ECO:0000269|PubMed:12444081, ECO:0000269|PubMed:17088532, ECO:0000269|PubMed:17095724, ECO:0000269|PubMed:24316715, ECO:0000269|PubMed:24407421}.
Subcellular Location	Nucleus, nucleolus. Nucleus speckle.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:11001926}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human WTAP gene - orb92119 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

WTAP - MBS1277662 from MyBioSource Species Human Accession BC000383

WTAP - MBS1265896 from MyBioSource Species Human Accession BC069192

Human WTAP ORF Clone(NM_004906.4) - CDCL181375 from Creative Biomart Species Human Accession NM_004906.4

human WTAP ORF clone - CDCH101580 from Creative Biomart Species Human Accession NM_004906

human WTAP ORF clone - CDCH101581 from Creative Biomart Species Human Accession NM_004906

human WTAP ORF clone - CDCH101582 from Creative Biomart Species Human Accession NM_004906

human WTAP ORF clone - CDCH101583 from Creative Biomart Species Human Accession NM_004906

Human WTAP Gene ORF cDNA clone in cloning vector - HG12018-G from Sino Biological Species Human

Human WTAP Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12018-CF from Sino Biological Species Human

Human WTAP Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12018-NM from Sino Biological Species Human

Human WTAP Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12018-CM from Sino Biological Species Human

Human WTAP Gene ORF cDNA clone expression plasmid, C-His tag - HG12018-CH from Sino Biological Species Human

Human WTAP Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12018-ACG from Sino Biological Species Human

Human WTAP Gene ORF cDNA clone expression plasmid - HG12018-UT from Sino Biological Species Human

Human WTAP Gene ORF cDNA clone expression plasmid, C-HA tag - HG12018-CY from Sino Biological Species Human

Human WTAP Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12018-G-F from Sino Biological Species Human

Human WTAP Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG12018-G-N from Sino Biological Species Human Accession NM_152857

Human WTAP Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG12018-ANG from Sino Biological Species Human

Human WTAP Gene ORF cDNA clone expression plasmid, N-HA tag - HG12018-NY from Sino Biological Species Human

Human WTAP Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12018-NF from Sino Biological Species Human

Human WTAP Gene ORF cDNA clone expression plasmid, N-His tag - HG12018-NH from Sino Biological Species Human

Human WTAP ORF Clone (BC000383) - CDCS412014 from Creative biogene Species Human Accession Q15007

Human WTAP ORF Clone (BC069192) - CDCS412015 from Creative biogene Species Human Accession Q15007

Human WTAP ORF clone (NM_152857) - CDCB160305 from Creative biogene Species Human

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