Gene Symbol |
Chrnb1
|
Entrez Gene |
11443
|
Alt Symbol |
Achr-2, Acrb
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
|
Other Description |
AChR beta|acetylcholine receptor beta|acetylcholine receptor subunit beta
|
Swissprots |
P09690 Q5F292
|
Accessions |
AAA37156 P09690 AK087554 BAC39924 BC023318 AAH23318 BY771238 CJ176855 M14537 AAA37154 XM_006532003 XP_006532066 XM_006532004 XP_006532067 XM_006532005 XP_006532068 NM_009601 NP_033731
|
Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
|
Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
Top Pathways |
Neuroactive ligand-receptor interaction
|