Gene Symbol | Ctsc |
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Entrez Gene | 13032 |
Alt Symbol | AI047818, DPP1, DPPI |
Species | Mouse |
Gene Type | protein-coding |
Description | cathepsin C |
Other Description | DPP-I|cathepsin J|dipeptidyl peptidase 1|dipeptidyl peptidase I|dipeptidyl transferase|dipeptidyl-peptidase 1|dipeptidyl-peptidase I|dipeptidylpeptidase 1 |
Swissprots | P97821 O08853 |
Accessions | EDL06795 EDL06796 P97821 AK002454 BAB22112 AK008910 AK049406 BAC33738 AK088398 BAC40328 AK146858 BAE27487 AK150761 BAE29829 AK151388 BAE30359 AK151711 AK151861 BAE30750 AK152192 BAE31022 AK152524 BAE31284 AK153168 AK167882 BAE39895 AK204397 AK207323 AK210964 AK215178 AK217142 BC067063 AAH67063 U74683 AAB58400 U89269 AAB49457 XM_006507319 XP_006507382 XM_006507320 XP_006507383 NM_009982 NP_034112 |
Function | Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the generation of cytotoxic lymphocyte effector function. |
Subcellular Location | Lysosome. |
Tissue Specificity | Broadly distributed, but higher levels found in lung, liver, kidney and spleen. Lower levels found in testis and brain. |
Top Pathways | Lysosome |
cathepsin C CRISPR/Cas9 KO Plasmid (m) - sc-419874 from Santa Cruz Biotechnology
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cathepsin C HDR Plasmid (m) - sc-419874-HDR from Santa Cruz Biotechnology
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cathepsin C Double Nickase Plasmid (m) - sc-419874-NIC from Santa Cruz Biotechnology
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cathepsin C Double Nickase Plasmid (m2) - sc-419874-NIC-2 from Santa Cruz Biotechnology
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cathepsin C CRISPR Activation Plasmid (m) - sc-419874-ACT from Santa Cruz Biotechnology
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cathepsin C CRISPR Activation Plasmid (m2) - sc-419874-ACT-2 from Santa Cruz Biotechnology
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cathepsin C Lentiviral Activation Particles (m) - sc-419874-LAC from Santa Cruz Biotechnology
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cathepsin C Lentiviral Activation Particles (m2) - sc-419874-LAC-2 from Santa Cruz Biotechnology
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cathepsin C siRNA (m) - sc-41472 from Santa Cruz Biotechnology
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cathepsin C shRNA Plasmid (m) - sc-41472-SH from Santa Cruz Biotechnology
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cathepsin C shRNA (m) Lentiviral Particles - sc-41472-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN29384 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29384 from Sigma-Aldrich
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CTSC siRNA (Mouse) - CRM0904 from Cohesion Biosciences
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CTSC - MBS8238789 from MyBioSource
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shRNA set against Mouse CTSC (NM_009982.4) - SHH271509 from Creative biogene
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shRNA set against Mouse Ctsc(NM_009982.4) - SHG172599 from Creative biogene
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CTSC shRNA Plasmid (Mouse) - CHM0904 from Cohesion Biosciences
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CTSC miRNA 3'UTR clone - MiUTR1M-03440 from Creative biogene
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