PPP2R1A

Gene Symbol PPP2R1A
Entrez Gene 5518
Alt Symbol PP2A-Aalpha, PP2AAALPHA, PR65A
Species Human
Gene Type protein-coding
Description protein phosphatase 2, regulatory subunit A, alpha
Other Description PP2A subunit A isoform PR65-alpha|PP2A subunit A isoform R1-alpha|medium tumor antigen-associated 61 KDA protein|protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform|serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform|serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
Swissprots Q6ICQ3 Q13773 Q96DH3 P30153
Accessions AAA35531 EAW72066 P30153 AK090488 BAG52168 AK091387 BAC03652 AK130000 AK290593 BAF83282 AK291932 BAF84621 AK293174 BAG56718 AK293493 BAG56980 AK299012 BAG61093 AK303934 BAG64862 AK307743 AK315700 BAG38062 AU128747 BC001537 AAH01537 BC026733 BT008074 AAP36766 CA426613 CR450340 CAG29336 DB246691 DC398468 DQ892756 ABM83682 DQ896000 ABM86978 J02902 AAA36399 NM_014225 NP_055040 NR_033500
Function The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis. {ECO:0000269|PubMed:16580887}.
Subcellular Location Cytoplasm {ECO:0000250}. Chromosome, centromere {ECO:0000269|PubMed:16580887}. Note=Centromeric localization requires the presence of BUB1.
Top Pathways Sphingolipid signaling pathway, Adrenergic signaling in cardiomyocytes, AMPK signaling pathway, Hippo signaling pathway, TGF-beta signaling pathway

PPP2R1A-Over-expression-Lysate - LY10569a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag PPP2R1A (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PPP2R1A gene (Lane 2, Cat. #LY10569a).

PPP2R1A 293 Cell Lysate - 402009 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

PPP2R1A Overexpression Lysate (Native) - NBL1-14692 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

PPP2R1A Over-expression Lysate Product - GWB-AB47E7 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

PPP2R1A Overexpression Lysate (Denatured) - H00005518-T02 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human PPP2R1A Knockdown Stable Cell Line - CSC-DC012270 from Creative biogene

Category Cell Line
Species Human
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