| Gene Symbol |
GNB1
|
| Entrez Gene |
2782
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
guanine nucleotide binding protein (G protein), beta polypeptide 1
|
| Other Description |
G protein, beta-1 subunit|beta subunit, signal-transducing proteins GS/GI|guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1|transducin beta chain 1
|
| Swissprots |
Q1RMY8 B1AJZ7 P62873
|
| Accessions |
EAW56147 EAW56148 EAW56149 EAW56150 P62873 AF070597 AAC28652 AF070603 AAC28655 AF501882 AAM15918 AI092255 AK096614 AK122949 BAG53814 AK312614 BAG35501 BC004186 AAH04186 BC005888 AAH05888 BC008991 AAH08991 BC114618 AAI14619 BC127205 BQ881467 BT007305 AAP35969 BU153593 BU684444 BU902364 CR456784 CAG33065 M36430 AAA63265 X04526 CAA28207 NM_001282538 NP_001269467 NM_001282539 NP_001269468 NM_002074 NP_002065
|
| Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. {ECO:0000269|PubMed:18611381}.
|
| Top Pathways |
PI3K-Akt signaling pathway, Circadian entrainment, Alcoholism, Retrograde endocannabinoid signaling, Chemokine signaling pathway
|