CD14

Gene Symbol CD14
Entrez Gene 929
Alt Symbol -
Species Human
Gene Type protein-coding
Description CD14 molecule
Other Description monocyte differentiation antigen CD14|myeloid cell-specific leucine-rich glycoprotein
Swissprots Q9UNS3 Q53XT5 Q96L99 P08571 Q96FR6
Accessions AAA20640 ADX31876 CAA29999 EAW62037 P08571 AB446505 BAG55282 AF097942 AAC83816 AK313277 BAG36085 AM392692 CAL37570 AM392824 CAL37702 AM393386 CAL38264 AM393697 CAL38573 AY044269 AAL02401 BC010507 AAH10507 BP300412 BT007331 AAP35995 CF593452 DA269805 DA426297 DA681405 M86511 AAA51930 W74441 X13334 CAA31711 NM_000591 NP_000582 NM_001040021 NP_001035110 NM_001174104 NP_001167575 NM_001174105 NP_001167576
Function In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. {ECO:0000269|PubMed:23264655}.
Subcellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
Top Pathways Legionellosis, Tuberculosis, Salmonella infection, Amoebiasis, Pertussis

CD14 CRISPR/Cas9 KO Plasmid (h) - sc-400344 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD14 HDR Plasmid (h) - sc-400344-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD14 Double Nickase Plasmid (h) - sc-400344-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD14 Double Nickase Plasmid (h2) - sc-400344-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD14 CRISPR Activation Plasmid (h) - sc-400344-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD14 CRISPR Activation Plasmid (h2) - sc-400344-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD14 Lentiviral Activation Particles (h) - sc-400344-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD14 Lentiviral Activation Particles (h2) - sc-400344-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD14 siRNA (h) - sc-29248 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD14 shRNA Plasmid (h) - sc-29248-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD14 shRNA (h) Lentiviral Particles - sc-29248-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU050931 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5679 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5679 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00368 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00368

CD14 siRNA (Human) - CRH0656 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD14 RNAi - H00000929-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CD14 - MBS8206163 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CD14 (NM_000591.3) - SHH258461 from Creative biogene

Category siRNA
Species Reactivities Human

CD14 shRNA Plasmid (Human) - CHH0656 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CD14 miRNA 3'UTR clone - MiUTR3H-01437 from Creative biogene

Species Reactivities Human

CD14 miRNA 3'UTR clone - MiUTR3H-01438 from Creative biogene

Species Reactivities Human
Search more