Htr1b

Gene Symbol Htr1b
Entrez Gene 15551
Alt Symbol -
Species Mouse
Gene Type protein-coding
Description 5-hydroxytryptamine (serotonin) receptor 1B
Other Description 5-HT-1B|5-HT1B receptor|5-HT<1B> receptor|5-hydroxytryptamine receptor 1B|serotonin receptor 1B
Swissprots P28334
Accessions AAA83221 CAA77678 EDL26441 P28334 BC119129 AAI19130 BC131951 AAI31952 NM_010482 NP_034612
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries. {ECO:0000269|PubMed:10651141, ECO:0000269|PubMed:1557407, ECO:0000269|PubMed:16750486, ECO:0000269|PubMed:8091214, ECO:0000269|PubMed:8742487, ECO:0000269|PubMed:9349547}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:1557407}; Multi-pass membrane protein {ECO:0000269|PubMed:1557407}.
Tissue Specificity Predominantly expressed in striatum and Purkinje cells. {ECO:0000269|PubMed:1557407}.
Top Pathways cAMP signaling pathway, Neuroactive ligand-receptor interaction

SR-1B (M-19) - sc-1461 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SR-1B (M-19): sc-1461. Western blot analysis of SR-1B expression in rat cerebellum (A) and mouse brain (B) tissue extracts.

HTR1B antibody - 70R-30612 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

5HT1B antibody - 70R-32258 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Serotonin receptor 1B (HTR1B) antibody - AP09879PU-N from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HTR1B antibody - STJ70929 from St John's Laboratory Ltd

Host Goat
Clonality Polyclonal

5HT1B, Polyclonal Antibody - MBS540154 from MyBioSource

Prices $390.00
Sizes 0.1 mg affinity-purified
Host Rabbit
Clonality Polyclonal

5HT1B Antibody - 5HT1B-201AP from FabGennix

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

5HT1B, Polyclonal Antibody - MBS540926 from MyBioSource

Prices $495.00
Sizes 0.1 mg biotin
Host Rabbit
Clonality Polyclonal

5HT1B, Polyclonal Antibody - MBS540927 from MyBioSource

Prices $495.00
Sizes 0.1 mg fitc
Host Rabbit
Clonality Polyclonal
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