OS9

Gene Symbol	OS9
Entrez Gene	10956
Alt Symbol	ERLEC2, OS-9
Species	Human
Gene Type	protein-coding
Description	osteosarcoma amplified 9, endoplasmic reticulum lectin
Other Description	amplified in osteosarcoma 9|endoplasmic reticulum lectin 2|erlectin 2|osteosarcoma amplified 9, endoplasmic reticulum associated protein|protein OS-9
Swissprots	A8K5Q9 E7ENT8 B4DE28 A6NDD1 Q8IZ58 B4E1I6 A6NLB2 A6NFR7 Q6IBL2 B4DPX1 G3XA88 O00579 F8VUH2 Q13438 Q9BW99 E7EW91
Accessions	AAC39523 BAA24362 EAW97044 EAW97045 EAW97046 EAW97047 Q13438 AB002806 BAA24363 AK129781 AK130733 AK291374 BAF84063 AK293435 BAG56939 AK294870 BAG57972 AK296770 BAG59349 AK298532 BAG60733 AK303291 BAH13933 AK303858 BAG64798 AK304533 BAG65333 AL137691 AU132426 BC000532 AAH00532 BC006506 AAH06506 BC007254 AAH07254 BC023513 AAH23513 BQ954079 CN335053 CR456791 CAG33072 DQ892759 ABM83685 DQ896004 ABM86982 EF036505 ABO65091 U09408 U41635 AAB06495 XM_005268581 XP_005268638 XM_006719200 XP_006719263 XM_006719201 XP_006719264 NM_001017956 NP_001017956 NM_001017957 NP_001017957 NM_001017958 NP_001017958 NM_001261420 NP_001248349 NM_001261421 NP_001248350 NM_001261422 NP_001248351 NM_001261423 NP_001248352 NM_006812 NP_006803
Function	Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4. {ECO:0000269|PubMed:17932042, ECO:0000269|PubMed:18264092, ECO:0000269|PubMed:18417469, ECO:0000269|PubMed:19084021, ECO:0000269|PubMed:19346256, ECO:0000269|PubMed:21172656}.
Subcellular Location	Endoplasmic reticulum lumen {ECO:0000269|PubMed:18264092, ECO:0000269|PubMed:18417469, ECO:0000269|PubMed:19084021}.
Tissue Specificity	Ubiquitously expressed. Found as well in all tumor cell lines analyzed, amplified in sarcomas. Highly expressed in osteosarcoma SJSA-1 and rhabdomyosarcoma Rh30 cell lines. Isoform 2 is the major isoform detected in all cell types examined.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human OS9 full length protein - ab132211 from Abcam Category Protein Source Wheat germ Species Human

Human OS9 peptide - ab23317 from Abcam Category Peptide

OS9 Antibody Blocking Peptide - LS-E4857 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

OS9 Antibody Blocking Peptide - LS-E16427 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

OS9 Blocking Peptide - NB100-519PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

OS9 Blocking Peptide - BC100-520PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

Recombinant Human OS9 Protein - H00010956-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

OS9-Antibody-C-term-Blocking-Peptide - BP17237b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

OS9 - H00010956-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

OS9 - H00010956-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

OS9 fusion protein - Ag0106 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human OS9, GST-tagged - OS9-1468H from Creative Biomart Category Protein Source E.coli Species Human

OS9 peptide - pep50004 from Covalab Category Peptide Species Human, Mouse, Rat

Recombinant Human Protein OS-9(OS9) - CSB-YP613402HU CSB-EP613402HU CSB-BP613402HU CSB-MP613402HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

OS9 (transcript variant 4) - TP316820 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

OS9 (transcript variant 1) - TP318206 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Osteosarcoma Amplified 9 (OS9) - RPC693Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Osteosarcoma Amplified 9 (OS9) - RPC693Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Osteosarcoma Amplified 9 (OS9) - RPC693Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

OS9 Recombinant Protein Antigen - NBP1-84803PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

OS9 Peptide, Human - M34GP11134H from Creative Peptides Category Peptide Source Synthetic. Species Human

Protein OS-9 (438-446) - ta-226 from Creative Peptides Category Protein Source Homo sapiens (human)

OS9 Recombinant Protein (OPCD00306) - OPCD00306 from Aviva Systems Biology Category Protein Source E.coli Species Human

Osteosarcoma Amplified 9, Recombinant Protein - MBS2034227 from MyBioSource Category Protein Prices $170.00, $345.00, $535.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic Expression Species Rat

Osteosarcoma Amplified 9, Recombinant Protein - MBS2034121 from MyBioSource Category Protein Prices $160.00, $320.00, $495.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic Expression Species Human

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