DHCR7

Gene Symbol DHCR7
Entrez Gene 1717
Alt Symbol SLOS
Species Human
Gene Type protein-coding
Description 7-dehydrocholesterol reductase
Other Description 7-DHC reductase|delta-7-dehydrocholesterol reductase|putative sterol reductase SR-2|sterol delta-7-reductase
Swissprots O60492 O60717 Q9UBM7 B2R6Z2
Accessions AAD24762 AAF06726 EAW74788 EAW74789 EAW74790 EAW74791 Q9UBM7 AF034544 AAC05086 AF062481 AAC18345 AF067127 AAD02816 AF096305 AAD09766 AI888720 AK289497 BAF82186 AK303881 BAG64817 AK309625 AK312775 BAG35639 BC000054 AAH00054 BU848891 DA502590 DQ891827 ABM82753 DQ895014 ABM85940 KJ534821 AHW56461 KJ534963 AHW56603 KJ534997 AHW56637 XM_011544777 XP_011543079 NM_001163817 NP_001157289 NM_001360 NP_001351
Function Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:9878250}; Multi-pass membrane protein {ECO:0000269|PubMed:9878250}.
Tissue Specificity Most abundant in adrenal gland, liver, testis, and brain. {ECO:0000269|PubMed:9878250}.
Top Pathways Steroid biosynthesis

DHCR7 CRISPR/Cas9 KO Plasmid (h) - sc-410538 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHCR7 HDR Plasmid (h) - sc-410538-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHCR7 Double Nickase Plasmid (h) - sc-410538-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHCR7 Double Nickase Plasmid (h2) - sc-410538-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHCR7 CRISPR Activation Plasmid (h) - sc-410538-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHCR7 CRISPR Activation Plasmid (h2) - sc-410538-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHCR7 Lentiviral Activation Particles (h) - sc-410538-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHCR7 Lentiviral Activation Particles (h2) - sc-410538-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHCR7 siRNA (h) - sc-60533 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DHCR7 shRNA Plasmid (h) - sc-60533-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DHCR7 shRNA (h) Lentiviral Particles - sc-60533-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DHCR7 RNAi - H00001717-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU059701 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7190 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7190 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DHCR7 siRNA (Human) - CRH1191 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DHCR7 - MBS8230056 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DHCR7 (NM_001360.2) - SHH277577 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human DHCR7(NM_001360.2) - SHH003395 from Creative biogene

Category siRNA
Species Reactivities Human

Human DHCR7 siRNA - orb261693 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DHCR7 shRNA Plasmid (Human) - CHH1191 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DHCR7 miRNA 3'UTR clone - MiUTR1H-02804 from Creative biogene

Species Reactivities Human

DHCR7 miRNA 3'UTR clone - MiUTR3H-05358 from Creative biogene

Species Reactivities Human
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