Gene Symbol | Srp14 |
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Entrez Gene | 20813 |
Alt Symbol | 14kDa, AW536328 |
Species | Mouse |
Gene Type | protein-coding |
Description | signal recognition particle 14 |
Other Description | (homologous Alu RNA binding protein)|homologous Alu RNA-binding protein|signal recognition particle 14 kDa protein |
Swissprots | Q3TIK2 P16254 |
Accessions | EDL27908 EDL27909 P16254 AK019310 BAB31658 AK156845 BAE33873 AK167821 BAE39844 AK168144 BAE40110 AV338114 BB848168 BC021537 AAH21537 CD774307 M29264 AAA40136 NM_009273 NP_033299 |
Function | Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. |
Subcellular Location | Cytoplasm. |
Top Pathways | Protein export |
SRP14 CRISPR/Cas9 KO Plasmid (m) - sc-423157 from Santa Cruz Biotechnology
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SRP14 HDR Plasmid (m) - sc-423157-HDR from Santa Cruz Biotechnology
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SRP14 Double Nickase Plasmid (m) - sc-423157-NIC from Santa Cruz Biotechnology
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SRP14 Double Nickase Plasmid (m2) - sc-423157-NIC-2 from Santa Cruz Biotechnology
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SRP14 CRISPR Activation Plasmid (m) - sc-423157-ACT from Santa Cruz Biotechnology
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SRP14 CRISPR Activation Plasmid (m2) - sc-423157-ACT-2 from Santa Cruz Biotechnology
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SRP14 Lentiviral Activation Particles (m) - sc-423157-LAC from Santa Cruz Biotechnology
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SRP14 Lentiviral Activation Particles (m2) - sc-423157-LAC-2 from Santa Cruz Biotechnology
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SRP14 siRNA (m) - sc-41362 from Santa Cruz Biotechnology
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SRP14 shRNA Plasmid (m) - sc-41362-SH from Santa Cruz Biotechnology
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SRP14 shRNA (m) Lentiviral Particles - sc-41362-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU072691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN42039 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42039 from Sigma-Aldrich
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SRP14 siRNA (Mouse) - CRM3917 from Cohesion Biosciences
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SRP14 - MBS8214257 from MyBioSource
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shRNA set against Mouse SRP14 (NM_009273.4) - SHH417900 from Creative biogene
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shRNA set against Mouse Srp14(NM_009273.4) - SHL034848 from Creative biogene
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Mouse SRP14 siRNA - orb283393 from Biorbyt
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SRP14 shRNA Plasmid (Mouse) - CHM3917 from Cohesion Biosciences
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SRP14 miRNA 3'UTR clone - MiUTR1M-11231 from Creative biogene
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