| Gene Symbol |
gnptab
|
| Entrez Gene |
553365
|
| Alt Symbol |
si:ch211-234f20.3, wu:fd55d09, zgc:122985, zgc:158502
|
| Species |
Zebrafish
|
| Gene Type |
protein-coding
|
| Description |
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
|
| Other Description |
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta|UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta|glcNAc-1-phosphotransferase subunits alpha/beta|stealth protein gnptab
|
| Swissprots |
Q568G1 Q5RGJ8
|
| Accessions |
Q5RGJ8 AW019667 BC092871 AAH92871 BC108017 AAI08018 BC133107 AAI33108 BF718021 XM_005164744 XP_005164801 NM_001044768 NP_001038233
|
| Function |
Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residues are required to bind to the M6P receptors (MPR), which mediate the vesicular transport of lysosomal enzymes to the endosomal/prelysosomal compartment (By similarity). {ECO:0000250}.
|
| Subcellular Location |
N-acetylglucosamine-1-phosphotransferase subunit alpha: Golgi apparatus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
|
| Top Pathways |
Lysosome
|