Gene Symbol | Atp6v1e1 |
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Entrez Gene | 11973 |
Alt Symbol | 2410029D23Rik, Atp6e, Atp6e2, Atp6v1e, D6Ertd385e, E2, P31, Vma4 |
Species | Mouse |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal V1 subunit E1 |
Other Description | ATPase, H+ transporting lysosomal (vacuolar proton pump), 32 kDa|ATPase, H+ transporting, V1 subunit E|ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E|H(+)-ATPase E-like protein|H+ ATPase subunit E|V-ATPase 31 kDa subunit|V-ATPase subunit E 1|V-type proton ATPase subunit E 1|VATPase, H+ transporting, lysosomal V1 subunit E1|lysosomal 31kDa|vacuolar proton pump subunit E 1 |
Swissprots | Q3UK59 Q8K5D6 P50518 Q99LD0 |
Accessions | AAC52412 EDK99645 EDK99646 P50518 AB074758 BAB92084 AK010603 AK029146 AK139791 AK146162 BAE26943 AK149356 BAE28832 AK167644 BAE39695 AK169854 BAE41412 AK186366 AK189499 AK189578 AK196381 AK198273 AK201997 AK203710 AK208012 BC003421 AAH03421 BC055438 AAH55438 NM_007510 NP_031536 |
Function | Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
Tissue Specificity | Expressed within the midpiece of sperm tail (at protein level). Ubiquitous. {ECO:0000269|PubMed:11872743, ECO:0000269|PubMed:23055941}. |
Top Pathways | Collecting duct acid secretion, Phagosome, Rheumatoid arthritis, Synaptic vesicle cycle, Oxidative phosphorylation |
ATP6E CRISPR/Cas9 KO Plasmid (m) - sc-419256 from Santa Cruz Biotechnology
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ATP6E HDR Plasmid (m) - sc-419256-HDR from Santa Cruz Biotechnology
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ATP6E Double Nickase Plasmid (m) - sc-419256-NIC from Santa Cruz Biotechnology
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ATP6E Double Nickase Plasmid (m2) - sc-419256-NIC-2 from Santa Cruz Biotechnology
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ATP6E CRISPR Activation Plasmid (m) - sc-419256-ACT from Santa Cruz Biotechnology
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ATP6E CRISPR Activation Plasmid (m2) - sc-419256-ACT-2 from Santa Cruz Biotechnology
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ATP6E Lentiviral Activation Particles (m) - sc-419256-LAC from Santa Cruz Biotechnology
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ATP6E Lentiviral Activation Particles (m2) - sc-419256-LAC-2 from Santa Cruz Biotechnology
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ATP6E siRNA (m) - sc-36794 from Santa Cruz Biotechnology
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ATP6E shRNA Plasmid (m) - sc-36794-SH from Santa Cruz Biotechnology
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ATP6E shRNA (m) Lentiviral Particles - sc-36794-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU002821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN27239 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27239 from Sigma-Aldrich
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ATP6V1E1 siRNA (Mouse) - CRM0311 from Cohesion Biosciences
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ATP6V1E1 - MBS8224194 from MyBioSource
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shRNA set against Mouse ATP6V1E1 (NM_007510.2) - SHH243170 from Creative biogene
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shRNA set against Mouse Atp6v1e1(NM_007510.2) - SHG083681 from Creative biogene
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Mouse ATP6V1E1 siRNA - orb279787 from Biorbyt
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ATP6V1E1 shRNA Plasmid (Mouse) - CHM0311 from Cohesion Biosciences
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ATP6V1E1 miRNA 3'UTR clone - MiUTR1M-01832 from Creative biogene
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