| Gene Symbol |
Parl
|
| Entrez Gene |
287979
|
| Alt Symbol |
Psarl
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
presenilin associated, rhomboid-like
|
| Other Description |
mitochondrial intramembrane-cleaving protease PARL|parl {ECO:0000250|UniProtKB:Q9H300}|presenilins-associated rhomboid-like protein, mitochondrial
|
| Swissprots |
Q3B8P0 Q5I0L2
|
| Accessions |
EDL77989 Q3B8P0 BC088226 AAH88226 BC105907 AAI05908 BC126098 BC158564 AAI58565 FQ214115 NM_001035249 NP_001030326
|
| Function |
Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|