| Gene Symbol |
Rgs9
|
| Entrez Gene |
29481
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
regulator of G-protein signaling 9
|
| Other Description |
-
|
| Swissprots |
P49805
|
| Accessions |
EDM06455 EDM06456 EDM06457 EDM06458 EDM06459 P49805 AB019145 BAA34051 AF038006 AAC01959 AF071475 AAC64039 U32433 AAC52370 NM_019224 NP_062097
|
| Function |
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Peripheral membrane protein. Note=Targeted to the membrane via its interaction with RGS9BP. {ECO:0000250}.
|
| Tissue Specificity |
Expressed in the central nervous system. Isoform RGS9L is found in striatum, hypothalamus and nucleus accumbens while isoform RGS9S is expressed in retina and pineal gland.
|
| Top Pathways |
Phototransduction, Cocaine addiction
|