ATG4C

Gene Symbol ATG4C
Entrez Gene 84938
Alt Symbol APG4-C, APG4C, AUTL1, AUTL3
Species Human
Gene Type protein-coding
Description autophagy related 4C, cysteine peptidase
Other Description APG4 autophagy 4 homolog C|ATG4 autophagy related 4 homolog C|AUT-like 1, cysteine endopeptidase|AUT-like 3 cysteine endopeptidase|autophagin-3|autophagy-related cysteine endopeptidase 3|autophagy-related protein 4 homolog C|cysteine protease ATG4C
Swissprots Q96DT6 A6NLR8 D3DQ58 Q96K04
Accessions EAX06579 EAX06580 Q96DT6 AJ312234 CAC85556 AJ320169 CAC43939 AK027773 BAB55356 BC008395 BC018678 AAH18678 BC033024 AAH33024 BI518482 BM146035 BM720875 BQ777265 DB183325 DQ892482 ABM83408 DQ895693 ABM86619 XM_005271288 XP_005271345 XM_011542313 XP_011540615 XM_011542314 XP_011540616 NM_032852 NP_116241 NM_178221 NP_835739
Function Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. {ECO:0000250, ECO:0000269|PubMed:21177865}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Highly expressed in skeletal muscle, heart, liver and testis. {ECO:0000269|PubMed:12446702}.
Top Pathways Regulation of autophagy

Cysteine protease ATG4C (ATG4C), Human, ELISA Kit - E01C1205 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Cysteine protease ATG4C (ATG4C), ELISA Kit - MBS7249479 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4C (ATG4C), ELISA Kit - MBS7227465 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4C (ATG4C), ELISA Kit - MBS7213416 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4C (ATG4C), ELISA Kit - MBS7209327 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4C (ATG4C), ELISA Kit - MBS7235735 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4C (ATG4C), ELISA Kit - MBS7206297 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4C (ATG4C), ELISA Kit - MBS7252645 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4C (ATG4C), ELISA Kit - MBS7222205 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4C (ATG4C), ELISA Kit - MBS7233215 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4C (ATG4C), ELISA Kit - MBS7238095 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4C (ATG4C), ELISA Kit - MBS7250424 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4C (ATG4C), ELISA Kit - MBS7212849 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human ATG4C ELISA Kit - E010807 from Biobool

Category ELISA Kit

anti-ATG4C antibody - ARG54819 from Arigo Biolaboratories

Category ELISA Kit
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