F13A1

Gene Symbol F13A1
Entrez Gene 2162
Alt Symbol F13A
Species Human
Gene Type protein-coding
Description coagulation factor XIII, A1 polypeptide
Other Description FSF, A subunit|TGase|bA525O21.1 (coagulation factor XIII, A1 polypeptide)|coagulation factor XIII A chain|coagulation factor XIII, A polypeptide|coagulation factor XIIIa|factor XIIIa|fibrin stabilizing factor, A subunit|fibrinoligase|protein-glutamine gamma-glutamyltransferase A chain|transglutaminase A chain|transglutaminase. plasma
Swissprots Q8N6X2 Q59HA7 Q96P24 P00488 Q9BX29
Accessions AAA52415 AAF65991 AAL12161 AAR97735 ABJ51931 CAA00294 EAW55185 EAW55186 P00488 AB208852 BAD92089 AK130666 AK304335 BAG65180 AK312735 BAG35606 BC027963 AAH27963 BP251770 DQ893561 ABM84487 DQ894109 ABM85035 EU176539 ABW03340 M14354 AAA52488 M14539 AAA52489 XM_006715010 XP_006715073 XM_011514342 XP_011512644 NM_000129 NP_000120
Function Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Subcellular Location Cytoplasm. Secreted. Note=Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.
Top Pathways Complement and coagulation cascades

Human Factor XIII full length protein - ab158413 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158413 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human Factor XIIIa full length protein - ab167813 from Abcam

Category Protein
Source Native
Species Human

Human Factor XIIIa full length protein - ab62412 from Abcam

Category Protein
Source Native
Species Human
Lane 1 : Non-reduced Factor XIIIa protein (ab62412) at 1 µg Lane 2 : Molecular weight standard Lane 3 : Reduced Factor XIIIa protein (ab62412) at 1 µg Notes: In the non-reduced sample the A chain shifts down toward the B chain following activation.

F13A1 / Factor XIIIa Antibody Blocking Peptide - LS-E26471 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

F13A1 / Factor XIIIa Antibody Blocking Peptide - LS-E26472 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Factor XIIIa Protein - H00002162-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Factor-XIIIa-Antibody-C-term-Blocking-Peptide - BP6735b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Factor XIIIa Peptide - AC21-1309-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

Coagulation factor XIIIa (F13A1) - H00002162-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Coagulation factor XIIIa (F13A1) - H00002162-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Factor XIII alpha Peptide - 45-564P from ProSci

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human

F13A1 fusion protein - Ag11105 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

F13A1 fusion protein - ag11059 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human F13A1, His-tagged - F13A1-12618H from Creative Biomart

Category Protein
Source E.coli
Species Human

Native Human F13A1 - F13A1-28806TH from Creative Biomart

Category Protein
Species Human

Native Human Coagulation Factor XIII, A1 Polypeptide - F13A1-5399H from Creative Biomart

Category Protein
Source Human plasma
Species Human

Native Human Coagulation Factor XIII, A1 Polypeptide - F13A1-1881H from Creative Biomart

Category Protein
Source Human plasma

Human coagulation Factor XIII - HFXIII from Molecular Innovations

Category Protein
Prices $360.00, $820.00
Sizes 250 µg, 1 mg
Species Human

Human coagulation Factor XIIIa - HFXIIIA from Molecular Innovations

Category Protein
Prices $405.00, $995.00
Sizes 250 µg, 1 mg
Source Human plasma
Species Human

Recombinant Coagulation Factor XIII A1 Polypeptide (F13A1) - RPB094Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Coagulation Factor XIII A1 Polypeptide (F13A1) - RPB094Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Coagulation Factor XIII A1 Polypeptide (F13A1) - RPB094Ra01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Rat

Coagulation Factor XIIIA (72-97) - 02180301 from MP Biomedicals

Prices $725.35
Sizes 1 mg

Factor XIII A Blocking Peptide - CBP1410 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Rat

Factor 13 A (G39) Peptide - BS7027P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl
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