ST3GAL1

Gene Symbol ST3GAL1
Entrez Gene 6482
Alt Symbol Gal-NAc6S, SIAT4A, SIATFL, ST3GalA, ST3GalA.1, ST3GalIA, ST3GalIA,1, ST3O
Species Human
Gene Type protein-coding
Description ST3 beta-galactoside alpha-2,3-sialyltransferase 1
Other Description CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1|Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase|SIAT4-A|ST3GalI|alpha 2,3-ST 1|beta-galactoside alpha-2,3-sialyltransferase 1|sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase)|sialyltransferase 4A (beta-galactoside alpha-2,3-sialyltransferase)|sialyltransferase 4A (beta-galactoside alpha-2,3-sialytransferase)
Swissprots O60677 Q9UN51 Q11201
Accessions CAS91688 EAW92172 EAW92173 EAW92174 Q11201 AF059321 AAC17874 AK093867 AK311319 AL709325 AL833743 BC018357 AAH18357 BC048803 BC063665 BX537506 BX648001 CN359425 DQ891156 ABM82082 DQ894335 ABM85261 L13972 AAC37574 L29555 AAA36612 XM_005251023 XP_005251080 XM_005251024 XP_005251081 XM_005251025 XP_005251082 XM_006716617 XP_006716680 XM_011517225 XP_011515527 XM_011517226 XP_011515528 NM_003033 NP_003024 NM_173344 NP_775479
Function It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O- linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values.
Subcellular Location Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane- bound form in trans cisternae of Golgi. Secreted into the body fluid.
Tissue Specificity Expressed in several tissues. Highest expression in lung, liver, skeletal muscle, kidney, pancreas, spleen and placenta.
Top Pathways Mucin type O-Glycan biosynthesis, Glycosaminoglycan biosynthesis - keratan sulfate, Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - ganglio series

Human SIAT4A full length protein - ab117048 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE stained with Coomassie Blue showing ab117048 at approximately 63.47 kDa.

Human SIAT4A protein fragment - ab152679 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab152679 stained with Coomassie Blue.

ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1/SIAT4A Recombinant Protein - H00006482-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1/SIAT4A Protein - H00006482-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human ST3GAL1, CF - 6905-GT-020 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Arg57-Arg340, with an N-terminal human CD33 signal and HA (YPYDVPDYA) tag

ST3GAL1 Blocking Peptide - 33R-10274 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

ST3GAL1 / SIAT4 - H00006482-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

ST3GAL1 / SIAT4 - H00006482-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

ST3GAL1 / SIAT4 - H00006482-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

ST3GAL1 / SIAT4 - H00006482-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Recombinant Human ST3GAL1 - ST3GAL1-29816TH from Creative Biomart

Category Protein
Source Wheat germ

Recombinant Human ST3GAL1 Protein, CF - 6905-GT from R&D Systems

Category Protein
Prices $359.00
Sizes 20 µg
Source Mouse myeloma cell line, NS0-derived Arg57-Arg340, with an N-terminal human CD33 signal and HA (YPYDVPDYA) tag
Species Human

ST3GAL1 / SIAT4 (transcript variant 1) - TP317696 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
ST3GAL1 / SIAT4

ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1/SIAT4A Recombinant Protein Antigen - NBP1-87045PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

ST3GAL1 Peptide, Human - M34GP15233H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

ST3Gal1, soluble fragment, Human Recombinant - P1224 from Biovision

Category Protein
Prices $175.00
Sizes 5 μg
Source Insect cells
Species Human

Recombinant Human ST3GAL1 Protein, CF - 6905-GT from Novus Biologicals

Category Protein
Prices $359.00
Sizes 20 µg
Species Human
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