ACSL1

Gene Symbol	ACSL1
Entrez Gene	2180
Alt Symbol	ACS1, FACL1, FACL2, LACS, LACS1, LACS2
Species	Human
Gene Type	protein-coding
Description	acyl-CoA synthetase long-chain family member 1
Other Description	LACS 1|LACS 2|acyl-CoA synthetase 1|fatty-acid-Coenzyme A ligase, long-chain 1|fatty-acid-Coenzyme A ligase, long-chain 2|lignoceroyl-CoA synthase|long-chain acyl-CoA synthetase 1|long-chain acyl-CoA synthetase 2|long-chain fatty acid-CoA ligase 2|long-chain fatty-acid-coenzyme A ligase 1|long-chain-fatty-acid--CoA ligase 1|palmitoyl-CoA ligase 1|palmitoyl-CoA ligase 2|paltimoyl-CoA ligase 1
Swissprots	Q8TA99 P41215 Q8N8V7 D3DP57 P33121 B7Z452
Accessions	CBF64949 CBU89820 EAX04662 EAX04663 EAX04664 EAX04665 P33121 AK096117 BAC04704 AK292798 BAF85487 AK296550 BAH12385 AK296826 BAH12438 AK303486 BAG64522 BC026290 AAH26290 BC033479 BC050073 AAH50073 BG680610 BG773086 BI461964 BM982557 D10040 BAA00931 DC344113 DQ083028 AAZ30711 DQ083029 AAZ30712 L09229 AAB00959 XM_005262828 XP_005262885 XM_005262829 XP_005262886 XM_005262831 XP_005262888 XM_011531740 XP_011530042 XM_011531741 XP_011530043 XM_011531742 XP_011530044 XM_011531743 XP_011530045 NM_001286708 NP_001273637 NM_001286710 NP_001273639 NM_001286711 NP_001273640 NM_001286712 NP_001273641 NM_001995 NP_001986
Function	Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate.
Subcellular Location	Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
Tissue Specificity	Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas. {ECO:0000269|PubMed:10548543}.
Top Pathways	Adipocytokine signaling pathway, PPAR signaling pathway, Peroxisome, Fatty acid biosynthesis, Fatty acid degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ACSL1 peptide - ab90244 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human ACSL1 protein fragment - ab116839 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

FACL2 / ACSL1 Antibody Blocking Peptide - LS-E11538 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FACL2 / ACSL1 Antibody Blocking Peptide - LS-E11537 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FACL2 / ACSL1 Antibody Blocking Peptide - LS-E31352 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ACSL1 Blocking Peptide - NB110-99585PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

Recombinant Human ACSL1 Protein - H00002180-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FACL4 blocking peptide - GTX89766-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat, Bovine

ACSL1 Blocking Peptide - 33R-3560 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ACSL1 Blocking Peptide - 33R-1349 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ACSL1 - H00002180-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ACSL1 - H00002180-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ACSL1 (Center) Control Peptide - AP55532CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

ACSL1 Peptide - 7081P from ProSci Category Peptide Species Human

ACSL1 fusion protein - Ag5059 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Recombinant Human Long-chain-fatty-acid--CoA ligase 1(ACSL1) - CSB-YP001191HU CSB-EP001191HU CSB-BP001191HU CSB-MP001191HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ACSL1 Recombinant Protein Antigen - NBP1-89271PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ACSL1 Protein - NBP1-89270PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

ACSL1-Blocking-Peptide-C-term - BP20275B from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ACSL1 Peptide, Human - M34GP00169H from Creative Peptides Category Peptide Source Synthetic. Species Human

Long-chain-fatty-acid--CoA ligase 1, Recombinant Protein - MBS7042059 from MyBioSource Category Protein Prices $1,485.00, $2,470.00, $3,675.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Long-chain-fatty-acid--CoA ligase 1 (ACSL1), Recombinant Protein - MBS959635 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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