PAX4

Gene Symbol PAX4
Entrez Gene 5078
Alt Symbol KPD, MODY9
Species Human
Gene Type protein-coding
Description paired box 4
Other Description paired box gene 4|paired box protein Pax-4|paired domain gene 4
Swissprots O95161 Q6B0H0 O43316
Accessions EAL24318 EAW83633 EAW83634 O43316 AB008913 BAA24506 AF043978 AAD02289 BC074761 AAH74761 BC107149 AAI07150 BC107150 AAI07151 DQ442656 ABD97848 EU446646 ABZ92175 XM_011516276 XP_011514578 NM_006193 NP_006184
Function Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.
Subcellular Location Nucleus.
Top Pathways Maturity onset diabetes of the young

Pax-4 (S-15) - sc-27832 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pax-4 (S-15): sc-27832. Western blot analysis of Pax-4 expression in HeLa (A), A-673 (B), SW480 (C) and K-562 (D) nuclear extracts.

Pax-4 (M-45) - sc-98942 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Pax-4 (M-45): sc-98942. Western blot analysis of Pax-4 expression in NIH/3T3 nuclear extract.

Pax-4 (H-60) - sc-98941 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Pax-4 (C-20) - sc-27833 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PAX4 antibody - ab42450 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Ab42450 at 4µg/ml staining human PAX4 in human epithelial cells of intestinal villus by immunohistochemistry, parafin embedded human intestine tissue.

Anti-PAX4 antibody - ab135598 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human brain tissue labelling PAX4 with ab135598 at 1/50 dilution followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-PAX4 antibody - ab101721 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-PAX4 antibody (ab101721) at 0.2 µg/ml + Mouse pancreas lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-PAX4 antibody - ab90674 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PAX4 antibody (ab90674) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal stomach lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PAX4 antibody [2F3] - ab170162 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F3
All lanes : Anti-PAX4 antibody [2F3] (ab170162) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY PAX4 cDNALysates/proteins at 5 µg per lane.

Anti-PAX4 antibody [3C12] - ab110026 from Abcam

Host Mouse
Clonality Monoclonal
Clone 3C12
All lanes : Anti-PAX4 antibody [3C12] (ab110026) at 1/500 dilutionLane 1 : HEK293 cell lysateLane 2 : PAX4-hIgGFc transfected HEK293 cell lysate

Anti-PAX4 antibody - C-terminal - ab200446 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PAX4 antibody - C-terminal (ab200446) at 1/1000 dilutionLane 1 : mouse thymus total cell extractLane 2 : Human Jurkat total cell extract

Anti-PAX4 Antibody (aa166-215) IHC-plus™ - LS-B3487 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PAX4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3487 concentration 5 ug/ml.

Anti-PAX4 Antibody (aa171-200) - LS-C163389 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with PAX4 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-PAX4 Antibody (aa201-215) - LS-C112973 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
PAX4 antibody (0.2 ug/ml) staining of Mouse Pancreas lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-PAX4 Antibody (aa35-84) - LS-C109706 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PAX4 antibody LS-C109706 Western blot of Fetal Stomach lysate.

Anti-PAX4 Antibody - LS-C341791 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PAX4 Antibody (clone 2F3) - LS-C175722 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F3
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PAX4 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PAX4.

Anti-PAX4 Antibody (aa1-228, clone 3H1) - LS-C336433 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3H1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PAX4 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PAX4.

Anti-PAX4 Antibody (aa1-228, clone 6H4) - LS-C336460 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6H4
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PAX4 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PAX4.

Anti-PAX4 Antibody (clone 3C12) - LS-C169305 from LifeSpan Bioscience

Prices $360.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3C12
Western blot using PAX4 monoclonal antibody against HEK293 (1) and PAX4(AA: 105-232)-hIgGFc transfected HEK293 (2) cell lysate.

Pax4 Antibody - AF2614 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

Pax4 Antibody - NBP1-49863 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: PAX4 Antibody [NBP1-49863] - Analysis of PAX4 in Mouse Pancreas lysate (35ug protein in RIPA buffer) using NBP1-49863 at 0.2ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Pax4 Antibody - NBP1-81043 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PAX4 Antibody [NBP1-81043] Staining of human cell line A-431 shows positivity in nuclei but not nucleoli.

Pax4 Antibody (3C12) - NBP2-37644 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3C12
Western Blot: Pax4 Antibody (3C12) [NBP2-37644] - Western blot analysis using PAX4 mAb against HEK293 (1) and PAX4(AA: 105-232)-hIgGFc transfected HEK293 (2) cell lysate.

Pax4 Antibody - NBP1-81044 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Pax4 Antibody [NBP1-81044] - Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.
Search more