| Gene Symbol |
dzip1
|
| Entrez Gene |
402875
|
| Alt Symbol |
igu, igu/dzip1, si:dz52i16.1
|
| Species |
Zebrafish
|
| Gene Type |
protein-coding
|
| Description |
DAZ interacting zinc finger protein 1
|
| Other Description |
DAZ interacting protein 1|DAZ-interacting protein 1 homolog|iguana protein|zin finger protein igu/dzip1|zinc finger protein Dzip1
|
| Swissprots |
Q8QFL8 Q7T019
|
| Accessions |
CAD24437 CAE30370 Q7T019 AB106357 BAC87859 AB106358 BAC87860 AY551927 AAS58471 BC162536 AAI62536 BC163603 AAI63603 XM_005165704 XP_005165761 XM_005165705 XP_005165762 XM_005165706 XP_005165763 XM_009302124 XP_009300399 NM_001001501 NP_001001501
|
| Function |
Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals. Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo. {ECO:0000269|PubMed:15115751, ECO:0000269|PubMed:15198976}.
|
| Subcellular Location |
Nucleus. Cytoplasm. Note=In the cytoplasm, it is localized in large vesicles. These vesicles correspond to lysosomes and/or endosomes. Can shuttle between the cytoplasm and the nucleus in a manner correlated with Hh activity.
|
| Tissue Specificity |
Expressed throughout the embryo starting at 12 hours. {ECO:0000269|PubMed:15115751}.
|