MTHFS

Gene Symbol MTHFS
Entrez Gene 10588
Alt Symbol HsT19268
Species Human
Gene Type protein-coding
Description 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
Other Description 5-formyltetrahydrofolate cyclo-ligase|methenyl-THF synthetase
Swissprots H3BQ75 P49914
Accessions EAW99132 P49914 AK054972 AL109717 AL110101 BC012417 AAH12417 BC019921 AAH19921 BC037852 BM313547 BM450865 CB995322 CK905549 DB464304 HG507300 L38928 AAC41945 NM_001199758 NP_001186687 NM_006441 NP_006432 NR_037654
Function Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10- methenyltetrahydrofolate. {ECO:0000269|PubMed:8522195}.
Subcellular Location Cytoplasm.
Top Pathways One carbon pool by folate

Human MTHFS full length protein - ab104635 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE analysis of 3µg ab104635.

Human MTHFS full length protein - ab124855 from Abcam

Category Protein
Source E. coli
Species Human

HsT19268 / MTHFS Antibody Blocking Peptide - LS-E6021 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

HsT19268 / MTHFS Antibody Blocking Peptide - LS-E18741 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

HsT19268 / MTHFS Antibody Blocking Peptide - LS-E18742 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

HsT19268 / MTHFS Antibody Blocking Peptide - LS-E26687 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

MTHFS Partial Recombinant Protein - H00010588-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 2 µg
Species Human

Recombinant Human MTHFS Protein - NBP1-51046 from Novus Biologicals

Category Protein
Prices $269.00, $729.00
Sizes 100 µg, 500 µg
Source E. coli
Species Human

MTHFS Recombinant Protein - P3574 from Novus Biologicals

Category Protein
Prices $549.00
Sizes 100 µg
Species Human

MTHFS-Antibody-C-term-Blocking-Peptide - BP18596b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

MTHFS blocking peptide - GTX88772-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse

Human MTHFS protein - orb246400 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Human MTHFS protein - orb168863 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 25 μg
Species Human

MTHFS Blocking Peptide - 33R-9307 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

MTHFS Blocking Peptide - 33R-9306 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

MTHFS protein (His tag) - 80R-1734 from Fitzgerald

Category Protein
Prices $255.00
Sizes 100 µg
Source E.coli

MTHFS Peptide - AC21-1527-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

MTHFS (1-203, His-tag) - AR09916PU-L from Acris Antibodies

Category Protein
Prices $790.00
Sizes 500 µg
Source E. coli
Species Human
MTHFS

MTHFS (1-203, His-tag) - AR09916PU-N from Acris Antibodies

Category Protein
Prices $340.00
Sizes 100 µg
Source E. coli
Species Human
MTHFS

MTHFS - H00010588-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

MTHFS - H00010588-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

MTHFS - P3574 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 100 µg
Species Human

5,10-Methenyltetrahydrofolate Synthetase, Human Recombinant - 228-12248-1 from RayBiotech

Category Protein
Prices $118.00
Sizes 1 µg
Source Escherichia Coli.
Species Human

MTHFS, 1-203aa, Human, His tag, E.coli - 01-P0976 from ARP American Research Products

Category Protein
Prices $179.00, $369.00, $849.00
Sizes 20 µg, 100 µg, 500 µg
Species Human

MTHFS Peptide - 46-871P from ProSci

Category Peptide
Species Human
Western blot analysis of MTHFS in Human Liver Lysate (35 μg protein in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide using MTHFS antibody (0.5 μg/mL).
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