| Gene Symbol |
Cyp27b1
|
| Entrez Gene |
13115
|
| Alt Symbol |
Cp2b, Cyp1, Cyp27b, Cyp40, P450c1, Pddr, Vdd1, Vddr, VddrI, Vdr
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 27, subfamily b, polypeptide 1
|
| Other Description |
1alpha(OH)ase|25(OH)D 1alpha-hydroxylase|25-OHD-1 alpha-hydroxylase|25-hydroxyvitamin D(3) 1-alpha-hydroxylase|25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial|25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial precursor (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D3 1-alpha-hydroxylase) (VD3 1A hydroxylase) (P450C1 alpha) (P450VD1-alpha)|25-hydroxyvitamin D3 1alpha-hydroxylase|P450VD1alpha|VD3 1A hydroxylase|calcidiol 1-monooxygenase|cytochrome P450 subfamily XXVIIB polypeptide 1|cytochrome P450, 27b1|cytochrome P450, 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase)|cytochrome P450C1 alpha|cytochrome P450VD1-alpha|cytochrome p450 27B1
|
| Swissprots |
O35084
|
| Accessions |
AAC05184 AAG44889 AAK15024 EDL24463 O35084 AB006034 BAA22434 BC080697 AAH80697 BM119774 CF168641 XM_006513187 XP_006513250 XM_011243350 XP_011241652 NM_010009 NP_034139
|
| Function |
Catalyzes the conversion of 25-hydroxyvitamin D3 (25(OH)D) to 1-alpha,25-dihydroxyvitamin D3 (1,25(OH)2D) plays an important role in normal bone growth, calcium metabolism, and tissue differentiation.
|
| Subcellular Location |
Mitochondrion membrane.
|
| Tissue Specificity |
Kidney.
|
| Top Pathways |
Tuberculosis, Steroid biosynthesis
|