| Gene Symbol |
DHODH
|
| Entrez Gene |
1723
|
| Alt Symbol |
DHOdehase, POADS, URA1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dihydroorotate dehydrogenase (quinone)
|
| Other Description |
dihydroorotate dehydrogenase (quinone), mitochondrial|dihydroorotate oxidase|human complement of yeast URA1
|
| Swissprots |
A8K8C8 Q02127 Q6P176
|
| Accessions |
EAW59198 EAW59199 EAW59200 EAW59201 Q02127 AI499306 AK097300 AK292293 BAF84982 AU130529 AU152444 BC065245 AAH65245 BE789211 BI253747 BM795077 M94065 AAA50163 XM_005255827 XP_005255884 XM_005255828 XP_005255885 XM_005255829 XP_005255886 NM_001361 NP_001352 NM_001025193
|
| Function |
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:10727948}; Single-pass membrane protein {ECO:0000269|PubMed:10727948}.
|
| Top Pathways |
Pyrimidine metabolism
|
![Western Blot: DHODH Overexpression Lysate (Adult Normal) [NBL1-09863] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DHODH.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9516_DHODH%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09863-img0002.jpg)