AQP3

Gene Symbol AQP3
Entrez Gene 360
Alt Symbol AQP-3, GIL
Species Human
Gene Type protein-coding
Description aquaporin 3 (Gill blood group)
Other Description aquaglyceroporin-3|aquaporin 3 (GIL blood group)|aquaporin-3
Swissprots B2RE16 Q92482 Q6FGW6 Q6FGT2 O00108 D3DRL3 A8K843
Accessions AAY68214 BAA09077 CCF76945 EAW58500 EAW58501 EAW58502 EAW58503 EAW58504 Q92482 AB001325 BAA19237 AJ493597 CAD38526 AK095363 AK292208 BAF84897 AK303206 BAG64296 AK315760 BAG38113 BC012988 BC013566 AAH13566 BF437236 BT007199 AAP35863 CR541991 CAG46788 CR542025 CAG46822 DA976040 XM_011517864 XP_011516166 NM_004925 NP_004916
Function Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism (By similarity). {ECO:0000250}.
Subcellular Location Basolateral cell membrane; Multi-pass membrane protein. Note=In collecting ducts of kidney.
Tissue Specificity Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level.
Top Pathways Vasopressin-regulated water reabsorption

Human-AQP3-cDNA-Clone - DC03644 from Abgent, a WuXi AppTec company

Prices $394.20
Sizes 10 µg
Species Human
Accession BC013566

AQP3 - MBS1272727 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC013566

Human AQP3 ORF Clone(NM_004925.4) - CDCL154191 from Creative Biomart

Species Human
Accession NM_004925.4

Human AQP3 ORF Clone (BC013566) - CDCS412022 from Creative biogene

Species Human
Accession Q92482
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