CYP26A1

Gene Symbol CYP26A1
Entrez Gene 1592
Alt Symbol CP26, CYP26, P450RAI, P450RAI1
Species Human
Gene Type protein-coding
Description cytochrome P450, family 26, subfamily A, polypeptide 1
Other Description P450, retinoic acid-inactivating, 1|cytochrome P450 26A1|cytochrome P450 retinoic acid-inactivating 1|cytochrome P450, subfamily XXVIA, polypeptide 1|cytochrome P450RAI|hP450RAI|retinoic acid 4-hydroxylase|retinoic acid-metabolizing cytochrome
Swissprots Q5VXH9 O43174 Q5VXI0 B3KNI4
Accessions EAW50078 EAW50079 O43174 AF005418 AAB88881 AK027560 BAG51346 AK075374 BC156283 AAI56284 BC157063 AAI57064 NM_000783 NP_000774 NM_057157 NP_476498
Function Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18- hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity Highest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain. {ECO:0000269|PubMed:9826557}.
Top Pathways Retinol metabolism

CYP26A1 CRISPR/Cas9 KO Plasmid (h) - sc-402832 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP26A1 HDR Plasmid (h) - sc-402832-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP26A1 Double Nickase Plasmid (h) - sc-402832-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP26A1 Double Nickase Plasmid (h2) - sc-402832-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP26A1 CRISPR Activation Plasmid (h) - sc-402832-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP26A1 CRISPR Activation Plasmid (h2) - sc-402832-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP26A1 Lentiviral Activation Particles (h) - sc-402832-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP26A1 Lentiviral Activation Particles (h2) - sc-402832-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP26A1 siRNA (h) - sc-72077 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP26A1 shRNA Plasmid (h) - sc-72077-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP26A1 shRNA (h) Lentiviral Particles - sc-72077-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP26A1 RNAi - H00001592-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU133401 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1809 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1809 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05524 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05524

CYP26A1 siRNA (Human) - CRH1119 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP26A1 RNAi - H00001592-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CYP26A1 - MBS8227700 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Cyp26a1 (NM_000783.3) - SHH272933 from Creative biogene

Category siRNA
Species Reactivities Human

CYP26A1 shRNA Plasmid (Human) - CHH1119 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CYP26A1 miRNA 3'UTR clone - MiUTR3H-04807 from Creative biogene

Species Reactivities Human

CYP26A1 miRNA 3'UTR clone - MiUTR3H-04808 from Creative biogene

Species Reactivities Human
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