| Gene Symbol |
ARSB
|
| Entrez Gene |
411
|
| Alt Symbol |
ASB, G4S, MPS6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
arylsulfatase B
|
| Other Description |
N-acetylgalactosamine-4-sulfatase
|
| Swissprots |
P15848 Q9UDI9 B2RC20 Q8N322
|
| Accessions |
AAB19988 CAA51272 EAW95821 EAW95822 EAW95823 P15848 AI244301 AI457798 AI821478 AK026942 AK290865 BAF83554 AK314903 BAG37417 AL135624 AW236748 BC029051 AAH29051 BC036609 BM664932 BQ216635 BQ775217 BX350102 BX364854 BX369127 J05225 AAA51784 M32373 AAA51779 XM_005248506 XP_005248563 XM_006714615 XP_006714678 XM_011543390 XP_011541692 XM_011543391 XP_011541693 XM_011543392 XP_011541694 XM_011543393 XP_011541695 NM_000046 NP_000037 NM_198709 NP_942002
|
| Function |
Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (PubMed:19306108). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (PubMed:19306108). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). {ECO:0000250|UniProtKB:P50430, ECO:0000269|PubMed:19306108}.
|
| Subcellular Location |
Lysosome. Cell surface {ECO:0000250|UniProtKB:P50429}.
|
| Top Pathways |
Lysosome, Glycosaminoglycan degradation
|
![Western Blot: ARSB Overexpression Lysate (Adult Normal) [NBL1-07737] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ARSB.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/11103_ARSB%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-07737-img0002.jpg)