Gene Symbol | NUDT5 |
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Entrez Gene | 11164 |
Alt Symbol | YSA1, YSA1H, YSAH1, hYSAH1 |
Species | Human |
Gene Type | protein-coding |
Description | nudix (nucleoside diphosphate linked moiety X)-type motif 5 |
Other Description | 8-oxo-dGDP phosphatase|ADP-sugar pyrophosphatase |
Swissprots | Q9UH49 A8K516 Q6IAG0 Q9UKK9 |
Accessions | EAW86320 EAW86321 EAW86322 Q9UKK9 AF155832 AAF06734 AF161464 AAF29079 AF218818 AAF25479 AK123731 AK291131 BAF83820 AK314144 BC000025 AAH00025 BU602000 CR457195 CAG33476 XM_011519304 XP_011517606 XM_011519305 XP_011517607 NM_014142 NP_054861 |
Function | Hydrolyzes with similar activities ADP-ribose ADP- mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. {ECO:0000269|PubMed:17052728}. |
Tissue Specificity | Widely expressed. Most abundant in liver. |
Top Pathways | Purine metabolism |
NUDT5 CRISPR/Cas9 KO Plasmid (h) - sc-407027 from Santa Cruz Biotechnology
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NUDT5 HDR Plasmid (h) - sc-407027-HDR from Santa Cruz Biotechnology
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NUDT5 Double Nickase Plasmid (h) - sc-407027-NIC from Santa Cruz Biotechnology
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NUDT5 Double Nickase Plasmid (h2) - sc-407027-NIC-2 from Santa Cruz Biotechnology
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NUDT5 CRISPR Activation Plasmid (h) - sc-407027-ACT from Santa Cruz Biotechnology
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NUDT5 CRISPR Activation Plasmid (h2) - sc-407027-ACT-2 from Santa Cruz Biotechnology
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NUDT5 Lentiviral Activation Particles (h) - sc-407027-LAC from Santa Cruz Biotechnology
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NUDT5 Lentiviral Activation Particles (h2) - sc-407027-LAC-2 from Santa Cruz Biotechnology
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NUDT5 siRNA (h) - sc-75973 from Santa Cruz Biotechnology
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NUDT5 shRNA Plasmid (h) - sc-75973-SH from Santa Cruz Biotechnology
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NUDT5 shRNA (h) Lentiviral Particles - sc-75973-V from Santa Cruz Biotechnology
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ADP-Sugar Pyrophosphatase/NUDT5 RNAi - H00011164-R01V from Novus Biologicals
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MISSION® esiRNA - EHU013191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15605 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15605 from Sigma-Aldrich
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NUDT5 siRNA (Human) - CRH7645 from Cohesion Biosciences
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ADP-Sugar Pyrophosphatase/NUDT5 RNAi - H00011164-R02 from Novus Biologicals
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shRNA set against Human NUDT5 (NM_014142.2) - SHH356208 from Creative biogene
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shRNA set against Human NUDT5(NM_014142.2) - SHR026034 from Creative biogene
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Human NUDT5 siRNA - orb268147 from Biorbyt
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NUDT5 shRNA Plasmid (Human) - CHH7645 from Cohesion Biosciences
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NUDT5 miRNA 3'UTR clone - MiUTR1H-06973 from Creative biogene
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