Gene Symbol | Ptprf |
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Entrez Gene | 19268 |
Alt Symbol | AA591035, LAR, LARS, RPTP-LAR |
Species | Mouse |
Gene Type | protein-coding |
Description | protein tyrosine phosphatase, receptor type, F |
Other Description | leukocyte antigen-related (LAR) PTP receptor|leukocyte common antigen related|receptor-type tyrosine-protein phosphatase F |
Swissprots | A2A8L5 Q6PG86 Q9EQ17 |
Accessions | A2A8L5 EDL30516 EDL30517 AF300943 AAG40194 AI385919 AK133085 BAE21505 AK135889 AK161629 BAE36501 BC039767 BC052322 BC057166 AAH57166 BU055092 BU056582 CA315396 CD352108 CK634962 CV556730 CX201972 Z23049 CAA80584 Z23061 CAA80596 Z37988 CAA86070 XM_006502864 XP_006502927 XM_006502865 XP_006502928 XM_006502866 XP_006502929 XM_006502867 XP_006502930 XM_006502868 XP_006502931 XM_006502869 XP_006502932 XM_006502870 XP_006502933 XM_006502871 XP_006502934 XM_006502872 XP_006502935 XM_006502874 XP_006502937 XM_006502875 XP_006502938 XM_006502876 XP_006502939 NM_011213 NP_035343 |
Function | Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in the cell of the T lineage but not in cells of any other hemopoietic lineage. {ECO:0000269|PubMed:11241288}. |
Top Pathways | Adherens junction, Cell adhesion molecules (CAMs), Insulin signaling pathway |
LAR CRISPR/Cas9 KO Plasmid (m) - sc-422521 from Santa Cruz Biotechnology
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LAR HDR Plasmid (m) - sc-422521-HDR from Santa Cruz Biotechnology
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LAR Double Nickase Plasmid (m) - sc-422521-NIC from Santa Cruz Biotechnology
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LAR Double Nickase Plasmid (m2) - sc-422521-NIC-2 from Santa Cruz Biotechnology
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LAR CRISPR Activation Plasmid (m) - sc-422521-ACT from Santa Cruz Biotechnology
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LAR CRISPR Activation Plasmid (m2) - sc-422521-ACT-2 from Santa Cruz Biotechnology
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LAR Lentiviral Activation Particles (m) - sc-422521-LAC from Santa Cruz Biotechnology
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LAR Lentiviral Activation Particles (m2) - sc-422521-LAC-2 from Santa Cruz Biotechnology
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LAR siRNA (m) - sc-35794 from Santa Cruz Biotechnology
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LAR shRNA Plasmid (m) - sc-35794-SH from Santa Cruz Biotechnology
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LAR shRNA (m) Lentiviral Particles - sc-35794-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU086111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN39649 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND39649 from Sigma-Aldrich
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PTPRF siRNA (Mouse) - CRM3330 from Cohesion Biosciences
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shRNA set against Mouse PTPRF (NM_011213.2) - SHH386712 from Creative biogene
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shRNA set against Mouse Ptprf(NM_011213.2) - SHH220002 from Creative biogene
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Mouse PTPRF siRNA - orb282806 from Biorbyt
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PTPRF shRNA Plasmid (Mouse) - CHM3330 from Cohesion Biosciences
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PTPRF miRNA 3'UTR clone - MiUTR1M-09771 from Creative biogene
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