ABCA3

Gene Symbol ABCA3
Entrez Gene 21
Alt Symbol ABC-C, ABC3, EST111653, LBM180, SMDP3
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family A (ABC1), member 3
Other Description ABC transporter 3|ABC-C transporter|ATP-binding cassette sub-family A member 3|ATP-binding cassette transporter 3
Swissprots Q99758 Q92473 B2RU09 Q6P5P9 Q54A95
Accessions AAY57325 EAW85515 Q99758 AB070929 BAB86781 AB210044 BAE06126 AK310864 BC020724 AAH20724 BC035752 BC062779 AAH62779 BC140895 AAI40896 BC146866 AAI46867 BC151840 AAI51841 BP397501 DA109409 U78735 AAC50967 X97187 CAA65825 NM_001089 NP_001080
Function Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Highly expressed in lung, followed by brain, pancreas, skeletal muscle and heart. Weakly expressed in placenta, kidney and liver. Also expressed in medullary thyroid carcinoma cells (MTC) and in C-cell carcinoma.
Top Pathways ABC transporters

ABCA3-Over-expression-Lysate - LY12275a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag ABCA3 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ABCA3 gene

ABCA3 Overexpression Lysate (Native) - NBP2-08442 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: ABCA3 Overexpression Lysate (Adult Normal) [NBP2-08442] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ABCA3.

Panoply™ Human ABCA3 Knockdown Stable Cell Line - CSC-DC000033 from Creative biogene

Category Cell Line
Species Human
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