Pla2g2c

Gene Symbol Pla2g2c
Entrez Gene 18781
Alt Symbol -
Species Mouse
Gene Type protein-coding
Description phospholipase A2, group IIC
Other Description 14 kDa phospholipase A2|GIIC sPLA2|PLA2-8|group IIC secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 2C|sPLA2-IIC
Swissprots P48076
Accessions EDL13275 P48076 BC029347 AAH29347 CA464794 U18119 AAC52936 NM_008868 NP_032894
Function PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Testis PA2 may be important in the production of prostaglandins, by the release of arachidonic acid, which in turn are necessary for the contractions of the seminiferous tubules and the testicular capsule; they also seem to decrease sperm transit time through the male reproductive tract.
Subcellular Location Secreted {ECO:0000305}.
Tissue Specificity Testis specific.
Top Pathways Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism

Mouse PLA2G2C ORF clone(NM_008868.3) - CDCG002215 from Creative biogene

Species Mouse
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