Gene Symbol |
ACAN
|
Entrez Gene |
280985
|
Alt Symbol |
AGC1
|
Species |
Bovine
|
Gene Type |
protein-coding
|
Description |
aggrecan
|
Other Description |
CSPCP|aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122)|aggrecan core protein|aggrecan epidermal growth factor-like domain-1|cartilage-specific proteoglycan core protein
|
Swissprots |
Q6XL66 P13608 Q28159 P79117
|
Accessions |
AAB48067 AAP44492 AAP44493 AAP44494 DAA17641 P13608 AF019755 AAC48797 U76615 AAB38524 XM_005221803 XP_005221860 XM_005221805 XP_005221862 XM_010816942 XP_010815244 NM_173981 NP_776406
|
Function |
This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000250}.
|