FMO2

Gene Symbol FMO2
Entrez Gene 2327
Alt Symbol FMO1B1
Species Human
Gene Type protein-coding
Description flavin containing monooxygenase 2 (non-functional)
Other Description FMO, pulmonary|dimethylaniline monooxygenase [N-oxide-forming] 2|dimethylaniline oxidase 2|pulmonary flavin-containing monooxygenase 2
Swissprots Q9BRX1 Q86U73 Q5EBX4 Q99518
Accessions AAW82431 EAW90889 Q99518 AI821378 AK098145 AK304385 BAG65221 AK312877 BAG35728 AL833218 CAI46191 BC005894 AAH05894 BI766311 BT006979 AAP35625 CA312067 DB224311 DB236882 DQ893533 ABM84459 DQ893748 ABM84674 R95468 Y09267 CAA70462 XR_426768 XR_921761 NM_001301347 NP_001288276 NM_001460 NP_001451
Function Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole. The truncated form is catalytically inactive. {ECO:0000269|PubMed:9804831}.
Subcellular Location Microsome membrane. Endoplasmic reticulum membrane.
Tissue Specificity Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain. {ECO:0000269|PubMed:11042094, ECO:0000269|PubMed:9804831}.
Top Pathways Drug metabolism - cytochrome P450

Human FMO2 ELISA Kit - E083479 from Biobool

Category ELISA Kit
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