Gene Symbol |
Arnt2
|
Entrez Gene |
11864
|
Alt Symbol |
Hif-2b, bHLHe1, mKIAA0307
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
aryl hydrocarbon receptor nuclear translocator 2
|
Other Description |
ARNT protein 2
|
Swissprots |
Q7TQG2 Q61324 Q8CHG9
|
Accessions |
EDL06859 EDL06860 Q61324 AB093225 BAC41409 AK032628 AK051629 AK194814 BC054546 AAH54546 BM115235 BU056629 D63644 BAA09799 XM_006507238 XP_006507301 XM_006507239 XP_006507302 XM_006507240 XP_006507303 XM_006507242 XP_006507305 XM_006507243 XP_006507306 XM_006507244 XP_006507307 XM_011241655 XP_011239957 NM_007488 NP_031514
|
Function |
Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function. Specifically recognizes the xenobiotic response element (XRE). {ECO:0000250|UniProtKB:Q9HBZ2}.
|
Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}.
|
Tissue Specificity |
Restricted to adult brain and kidney.
|
Top Pathways |
Renal cell carcinoma, Transcriptional misregulation in cancer
|