Gene Symbol | Phb |
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Entrez Gene | 18673 |
Alt Symbol | Bap32 |
Species | Mouse |
Gene Type | protein-coding |
Description | prohibitin |
Other Description | B-cell receptor-associated protein 32 |
Swissprots | Q5SQG4 Q3UB75 P67778 |
Accessions | EDL15986 EDL15987 P67778 AK002714 BAB22305 AK010619 BAB27067 AK150956 BAE29988 AK151073 BAE30089 AK152933 AK160490 BAE35821 AK168248 BAE40198 AK168656 BAE40512 AK178178 AK180942 AK182772 AK190324 AK190335 AK205895 AW457788 BC083354 AAH83354 BC089034 AAH89034 BM935516 BY333636 X78682 CAA55349 NM_008831 NP_032857 |
Function | Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:11302691}. |
Tissue Specificity | Widely expressed in different tissues. {ECO:0000269|PubMed:8070406}. |
Prohibitin CRISPR/Cas9 KO Plasmid (m) - sc-422218 from Santa Cruz Biotechnology
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Prohibitin HDR Plasmid (m) - sc-422218-HDR from Santa Cruz Biotechnology
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Prohibitin Double Nickase Plasmid (m) - sc-422218-NIC from Santa Cruz Biotechnology
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Prohibitin Double Nickase Plasmid (m2) - sc-422218-NIC-2 from Santa Cruz Biotechnology
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Prohibitin CRISPR Activation Plasmid (m) - sc-422218-ACT from Santa Cruz Biotechnology
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Prohibitin CRISPR Activation Plasmid (m2) - sc-422218-ACT-2 from Santa Cruz Biotechnology
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Prohibitin Lentiviral Activation Particles (m) - sc-422218-LAC from Santa Cruz Biotechnology
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Prohibitin Lentiviral Activation Particles (m2) - sc-422218-LAC-2 from Santa Cruz Biotechnology
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Prohibitin siRNA (m) - sc-37630 from Santa Cruz Biotechnology
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Prohibitin shRNA Plasmid (m) - sc-37630-SH from Santa Cruz Biotechnology
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Prohibitin shRNA (m) Lentiviral Particles - sc-37630-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU202201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN38629 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND38629 from Sigma-Aldrich
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PHB siRNA (Mouse) - CRM3048 from Cohesion Biosciences
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shRNA set against Mouse PHB (NM_008831.4) - SHH374528 from Creative biogene
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Mouse PHB siRNA - orb282524 from Biorbyt
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PHB shRNA Plasmid (Mouse) - CHM3048 from Cohesion Biosciences
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