Gene Symbol | GTF2E1 |
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Entrez Gene | 2960 |
Alt Symbol | FE, TF2E1, TFIIE-A |
Species | Human |
Gene Type | protein-coding |
Description | general transcription factor IIE, polypeptide 1, alpha 56kDa |
Other Description | TFIIE-alpha|general transcription factor IIE 56 kDa subunit|general transcription factor IIE subunit 1|transcription initiation factor IIE subunit alpha |
Swissprots | P29083 Q16103 |
Accessions | EAW79519 P29083 AK223401 BAD97121 BC005917 AAH05917 BC156224 AAI56225 BC156997 AAI56998 DA498425 S67859 AAB20413 X63468 CAA45068 XM_011512744 XP_011511046 XM_011512745 XP_011511047 NM_005513 NP_005504 |
Function | Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. |
Subcellular Location | Nucleus. |
Top Pathways | Viral carcinogenesis, Epstein-Barr virus infection, Basal transcription factors |
TFIIE-α CRISPR/Cas9 KO Plasmid (h) - sc-404654 from Santa Cruz Biotechnology
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TFIIE-α HDR Plasmid (h) - sc-404654-HDR from Santa Cruz Biotechnology
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TFIIE-α Double Nickase Plasmid (h) - sc-404654-NIC from Santa Cruz Biotechnology
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TFIIE-α Double Nickase Plasmid (h2) - sc-404654-NIC-2 from Santa Cruz Biotechnology
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TFIIE-α CRISPR Activation Plasmid (h) - sc-404654-ACT from Santa Cruz Biotechnology
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TFIIE-α CRISPR Activation Plasmid (h2) - sc-404654-ACT-2 from Santa Cruz Biotechnology
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TFIIE-α Lentiviral Activation Particles (h) - sc-404654-LAC from Santa Cruz Biotechnology
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TFIIE-α Lentiviral Activation Particles (h2) - sc-404654-LAC-2 from Santa Cruz Biotechnology
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TFIIE-α siRNA (h) - sc-36651 from Santa Cruz Biotechnology
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TFIIE-α shRNA Plasmid (h) - sc-36651-SH from Santa Cruz Biotechnology
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TFIIE-α shRNA (h) Lentiviral Particles - sc-36651-V from Santa Cruz Biotechnology
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TFIIE-alpha RNAi - H00002960-R01 from Novus Biologicals
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MISSION® esiRNA - EHU017271 from Sigma-Aldrich
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MISSION® esiRNA - EHU103151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9757 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9757 from Sigma-Aldrich
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GTF2E1 siRNA (Human) - CRH2003 from Cohesion Biosciences
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GTF2E1 - MBS8207468 from MyBioSource
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shRNA set against Human GTF2E1(NM_005513.2) - SHH108479 from Creative biogene
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Human GTF2E1 siRNA - orb262505 from Biorbyt
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GTF2E1 shRNA Plasmid (Human) - CHH2003 from Cohesion Biosciences
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GTF2E1 miRNA 3'UTR clone - MiUTR3H-02245 from Creative biogene
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