CD58

Gene Symbol CD58
Entrez Gene 965
Alt Symbol LFA-3, LFA3, ag3
Species Human
Gene Type protein-coding
Description CD58 molecule
Other Description CD58 antigen, (lymphocyte function-associated antigen 3)|lymphocyte function-associated antigen 3|surface glycoprotein LFA-3
Swissprots A8K7G5 P19256 Q96KI9 Q6IB65 Q5U053
Accessions CAA75083 CAA75084 CAJ86521 CBX51827 CDM22273 EAW56652 EAW56653 EAW56654 EAW56655 EAW56656 P19256 AK125710 AK291980 BAF84669 BC005930 AAH05930 BT019816 AAV38619 BT019817 AAV38620 CA312671 CD365881 CR456939 CAG33220 D28586 BAA05922 EF491785 S79616 AAB40000 X06296 CAA29622 Y00636 CAA68668 NM_001144822 NP_001138294 NM_001779 NP_001770 NR_026665
Function Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen- presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Subcellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein.
Top Pathways Cell adhesion molecules (CAMs), Epstein-Barr virus infection

CD58 (TS2/9.1.4.3) - sc-20009 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD58 (TS2/9.1.4.3): sc-20009. Indirect FCM analysis of Jurkat cells stained with CD58 (TS2/9.1.4.3), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-3877.

CD58 (C-20) - sc-6983 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CD58 (FL-250) - sc-20925 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD58 (FL-250): sc-20925. Western blot analysis of CD58 expression in Jurkat (A) and TF-1 (B) whole cell lysates.

CD58 (HCD58) - sc-53670 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CD58 (HCD58): sc-53670. Western blot analysis of CD58 expression in HeLa (A), human PBL (B) and Raji (C) whole cell lysates.

CD58 (TS2/9) - sc-81734 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Anti-LFA3 antibody - ab110379 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LFA3 antibody (ab110379) at 1/500 dilutionLane 1 : Extracts from HuvEc cellsLane 2 : Extracts from HuvEc cells with blocking peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-LFA3 antibody - ab128653 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-LFA3 antibody (ab128653) at 1 µg/ml + COLO205 cell lysate at 10 µg

Anti-LFA3 antibody [2D11-B10] - ab117626 from Abcam

Prices $464.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2D11-B10
ELISA showing the detection limit for recombinant proprietary tagged LFA3 is approximately 0.3ng/ml as a capture antibody (ab117626).

Anti-LFA3 antibody [B-L28] - ab47070 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-L28
A typical staining pattern with the B-L28 monoclonal antibody of lymphocytes

Anti-LFA3 antibody [B-L28] (Phycoerythrin) - ab27301 from Abcam

Prices $216.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone B-L28
A typical staining pattern with ab27301 (10 µl per 106 cells or 100 µl of whole blood) of lymphocytes.

Anti-LFA3 antibody [EP15041] - ab196648 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP15041
All lanes : Anti-LFA3 antibody [EP15041] (ab196648) at 1/5000 dilutionLane 1 : Raji (Human Burkitt's lymphoma cell line) whole cell lysateLane 2 : Jurkat (Human T cell leukemia cells from peripheral blood) whole cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-LFA3 antibody [HI58a] (Allophycocyanin) - ab91058 from Abcam

Prices $216.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone HI58a

Anti-LFA3 antibody [HI58a] (CF405M) - ab117738 from Abcam

Prices $216.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone HI58a
Staining of normal Human peripheral blood cells with ab117738. Cells in the Lymphocytes gate were used for analysis (red histogram).

Anti-LFA3 antibody [MEM-63] (Allophycocyanin) - ab180550 from Abcam

Prices $357.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone MEM-63

Anti-LFA3 antibody [MEM-63] (Biotin) - ab21897 from Abcam

Prices $216.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MEM-63

Anti-LFA3 antibody [MEM-63] (FITC) - ab26006 from Abcam

Prices $165.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone MEM-63

Anti-LFA3 antibody [MM0176-8G24] - ab89157 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone MM0176-8G24

Anti-LFA3 antibody [TS2/9] - ab171087 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone TS2/9
Immunofluorescent analysis of LFA3 (green) showing staining in the cytoplasm of Raji cells (right) compared to a negative control without primary antibody (left). Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with a LFA3 monoclonal antibody (ab171087) in 3% BSA-PBS at a dilution of 1:20 and incubated overnight at 4ºC in a humidified chamber. Cells were washed with PBST and incubated with a DyLight-conjugated secondary antibody in PBS at room temperature in the dark. F-actin (red) was stained with a fluorescent red phalloidin and nuclei (blue) were stained with Hoechst or DAPI. Images were taken at a magnification of 60x.

Human LFA3 protein fragment - ab187438 from Abcam

Prices $442.00
Sizes 100 µg
15% SDS-PAGE analysis of 3 µg of ab187438.

Anti-CD58 Antibody (clone 2D11-B10) IHC-plus™ - LS-B5386 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2D11-B10
Anti-CD58 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5386 concentration 5 ug/ml.

Anti-CD58 Antibody (FITC) - LS-C5415 from LifeSpan Bioscience

Prices $415.00
Sizes 50 tst
Host Mouse
Clonality Monoclonal

Anti-CD58 Antibody - LS-C5414 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CD58 Antibody (PE) - LS-C5416 from LifeSpan Bioscience

Prices $415.00
Sizes 50 tst
Host Mouse
Clonality Monoclonal

Anti-CD58 Antibody (Cytoplasmic Domain) - LS-C5409 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CD58 Antibody (PE, Cy5) - LS-C5417 from LifeSpan Bioscience

Prices $415.00
Sizes 50 tst
Host Mouse
Clonality Monoclonal
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