RQCD1

Gene Symbol RQCD1
Entrez Gene 9125
Alt Symbol CNOT9, CT129, RCD-1, RCD1
Species Human
Gene Type protein-coding
Description RCD1 required for cell differentiation1 homolog (S. pombe)
Other Description CCR4-NOT transcription complex subunit 9|cancer/testis antigen 129|cell differentiation protein RCD1 homolog|protein involved in sexual development
Swissprots Q92600 Q96IX4 B2RPI0 B5MDQ4 B7Z1E5
Accessions BAA13508 EAW70624 EAW70625 Q92600 AA806815 AB500892 BAJ07307 AK293281 BAH11481 AK296037 BAG58803 AK316567 BAG38156 BC007102 AAH07102 BC137455 AAI37456 BC137456 AAI37457 DC299874 XM_011512138 XP_011510440 NM_001271634 NP_001258563 NM_001271635 NP_001258564 NM_005444 NP_005435 NR_073390
Function Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all. {ECO:0000250, ECO:0000269|PubMed:17189474, ECO:0000269|PubMed:18180299}.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm, P-body {ECO:0000250}. Note=NANOS2 promotes its localization to P-body. {ECO:0000250}.
Tissue Specificity Detected in spleen, thymus, prostate, testis, ovary and intestine. {ECO:0000269|PubMed:9447985}.
Top Pathways RNA degradation

RQCD1 (P-14) - sc-169224 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RQCD1 (T-14) - sc-169225 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-RQCD1 antibody - ab173563 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-RQCD1 antibody (ab173563) at 1/100 dilution + Mouse cerebellum tissue lysates at 35 µg

Anti-RQCD1 antibody - ab130397 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Formalin-fixed, paraffin embedded Human duodenum tissue labelled with RQCD1 antibody at 1/20 dilution.

Anti-RQCD1 antibody - N-terminal - ab199939 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-RQCD1 antibody - N-terminal (ab199939) at 1/1000 dilutionLane 1 : Mouse brain total cell extractLane 2 : Mouse thymus total cell extract

Anti-RCD1 / RQCD1 Antibody (aa106-134, APC) - LS-C268584 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RCD1 / RQCD1 Antibody (aa106-134, FITC) - LS-C268587 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RCD1 / RQCD1 Antibody (aa106-134, PE) - LS-C268590 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RCD1 / RQCD1 Antibody (aa106-134, Azide-free, HRP) - LS-C268588 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RCD1 / RQCD1 Antibody (aa105-134) - LS-C324834 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RCD1 / RQCD1 Antibody (aa139-188) - LS-C186792 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human 721_B. RQCD1 antibody dilution 1.0 ug/ml.

Anti-RCD1 / RQCD1 Antibody (aa106-134) - LS-C158897 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RQCD1 Antibody western blot of mouse cerebellum tissue lysates (35 ug/lane). The RQCD1 antibody detected the RQCD1 protein (arrow).

Anti-RCD1 / RQCD1 Antibody (aa106-134, Biotin) - LS-C268586 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RCD1 / RQCD1 Antibody (aa106-134, AP) - LS-C268583 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

RQCD1 Antibody - NBP1-92354 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: RQCD1 Antibody [NBP1-92354] Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

ANTI-RQCD1 (CENTER) antibody produced in rabbit - SAB1302651 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RQCD1 (Center): <B>Cat. No. SAB1302651</B>: RQCD1 Antibody (Center) western blot analysis in MDA-MB-231 cell line lysates (35 μg/lane).

Anti-RQCD1 antibody produced in rabbit - HPA046622 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RQCD1: <B>Cat. No. HPA046622</B>: Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

RQCD1 Antibody - middle region (ARP66266_P050) - ARP66266_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RQCD1-Antibody-Center - AP17848c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
RQCD1 Antibody (Center) (Cat. #AP17848c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RQCD1 antibody detected the RQCD1 protein (arrow).

RQCD1 Antibody - middle region (OAAB13278) - OAAB13278 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

RQCD1 Antibody - abx029822 from Abbexa

Host Rabbit
Clonality Polyclonal

RQCD1 antibody - 22503-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human small intestine slide using 22503-1-AP( RQCD1 Antibody) at dilution of 1:50

Rabbit Anti-RQCD1 (Center) - 102-13563 from RayBiotech

Host Rabbit
RQCD1 Antibody (Center) (Cat# 102-13563) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RQCD1 antibody detected the RQCD1 protein (arrow).

RQCD1 antibody (Center) - STJ46141 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal
Clone RB37988

RQCD1 antibody - 22503-1-AP from Proteintech Group

Prices $279.00
Sizes con: 55 μg/150μl
Host Rabbit
Clonality Polyclonal
mouse thymus tissue were subjected to SDS PAGE followed by western blot with 22503-1-AP(RQCD1 antibody) at dilution of 1:1000
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