| Gene Symbol |
Tff3
|
| Entrez Gene |
25563
|
| Alt Symbol |
ITF
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
trefoil factor 3, intestinal
|
| Other Description |
intestinal trefoil factor|polypeptide P1.B|trefoil factor 3
|
| Swissprots |
Q03191 Q68FZ2
|
| Accessions |
EDL96998 Q03191 AF012534 AAB71352 BC078873 AAH78873 BP490107 M80826 AAA42270 S49317 AAB24079 U48825 AAC52439 X66956 CAA47378 NM_013042 NP_037174
|
| Function |
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:1763017, ECO:0000269|PubMed:9299425}. Cytoplasm {ECO:0000250|UniProtKB:Q07654}.
|
| Tissue Specificity |
Expressed in goblet cells of the intestines, and colon, in paraventricular hypothalamus and supraoptic nuclei. Weakly expressed in gastric epithelial cells (at protein level). Expressed by goblet cells of small and large intestinal epithelia, kidney and stomach. Expressed in the paraventricular hypothalamus, arcuate nucleus and amygdala of the brain. Weakly expressed in gastric epithelial cells. {ECO:0000269|PubMed:1637322, ECO:0000269|PubMed:1763017, ECO:0000269|PubMed:19076725, ECO:0000269|PubMed:8454642, ECO:0000269|PubMed:8750886}.
|