CAV1

Gene Symbol	CAV1
Entrez Gene	857
Alt Symbol	BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21
Species	Human
Gene Type	protein-coding
Description	caveolin 1, caveolae protein, 22kDa
Other Description	caveolin-1|cell growth-inhibiting protein 32
Swissprots	Q9UQH6 Q9UGP1 Q9UNG1 Q03135
Accessions	AAB82538 AAD23745 AAD34722 CAB63654 EAL24360 EAW83503 EAW83504 EAW83505 Q03135 AB209926 BAD93163 AB451284 BAG70098 AB451416 BAG70230 AF070648 AF074993 AF172085 AAQ13608 AI878826 AK290871 BAF83560 AK307501 AL133639 AM393679 CAL38555 AY762103 AAX07830 BC006432 BC009685 AAH09685 BC082246 AAH82246 BG170208 BT007143 AAP35807 DA477166 DA943080 DB266251 DQ890647 ABM81573 DQ893827 ABM84753 EF179102 EF649773 ABW22625 EF649774 ABW22626 EU176473 ABW03274 Z18951 CAA79476 NM_001172895 NP_001166366 NM_001172896 NP_001166367 NM_001172897 NP_001166368 NM_001753 NP_001744
Function	May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. {ECO:0000250, ECO:0000269|PubMed:11751885, ECO:0000269|PubMed:17287217}.
Subcellular Location	Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin- like structure in the membrane. Membrane protein of caveolae.
Tissue Specificity	Expressed in muscle and lung, less so in liver, brain and kidney.
Top Pathways	Focal adhesion, Endocytosis, Bacterial invasion of epithelial cells, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PathScan ® Total Caveolin-1 Sandwich ELISA Kit - 12384 from Cell Signaling Technology Category ELISA Kit Prices $489.00 Sizes 1 kit (96 assays)

Rat CAV1 / Caveolin 1 ELISA Kit (Sandwich ELISA) - LS-F5221 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.055 ng/ml Range 0.234-15 ng/ml

Dog CAV1 / Caveolin 1 ELISA Kit (Sandwich ELISA) - LS-F6015 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 32 pg/ml Range 0.234-15 ng/ml

Chicken CAV1 / Caveolin 1 ELISA Kit (Sandwich ELISA) - LS-F6016 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.064 ng/ml Range 0.234-15 ng/ml

Human CAV1 / Caveolin 1 ELISA Kit (Sandwich ELISA) - LS-F4689 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.09 ng/ml Range 0.234-15 ng/ml

Mouse/Human/Rat CAV1 / Caveolin 1 ELISA Kit (Cell-Based ELISA) - LS-F1862 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.234-15 ng/ml

Mouse/Human/Rat Phospho-CAV1 / Caveolin 1 (Tyr14) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1467 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.234-15 ng/ml

Human CAV1 / Caveolin 1 ELISA Kit (Sandwich ELISA) - LS-F11036 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.234-15 ng/ml

Human Caveolin-1 ELISA Kit - abx051646 from Abbexa Category ELISA Kit Sensitivity 22 pg/ml Range 80 pg/ml - 3000 pg/ml

Caveolin-1, Cav-1, Human, ELISA Kit - E-EL-H0673 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Caveolin-1, Cav-1, Human, ELISA Kit - CSB-E09682h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 7.8 pg/ml Range 31.25 pg/ml-2000 pg/ml

Caveolin-1, CAV1, Human, ELISA Kit - E0214h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Caveolin 1 kit, CAV1, Mouse, ELISA Kit - E-EL-M0253 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 23.438 Range 39.063-2500pg/mL

Caveolin-1, CAV-1, Rat, ELISA Kit - E-EL-R0175 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Caveolin-1, Cav-1, Rabbit, ELISA Kit - E-EL-RB1076 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 28.125 Range 46.875-3000pg/mL

Caveolin-1, Cav-1, Chicken, ELISA Kit - E-EL-Ch1903 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

Caveolin-1, Cav-1, Porcine, ELISA Kit - E-EL-P2044 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Caveolin-1, Cav-1, Guinea Pig, ELISA Kit - E-EL-GP0775 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Caveolin-1, Cav-1, Monkey, ELISA Kit - E-EL-MK1433 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 46.875 Range 78.125-5000pg/mL

Human Cav-1 ELISA Kit - HC0707 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human CAV1 ELISA Kit - HC0414 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine CAV1 ELISA Kit - AC0414 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine Cav-1 ELISA Kit - AC0707 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

CAV1, ELISA Kit - MBS2510875 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 23.438pg/mL Range 39.063--2500pg/mL

Caveolin 1, ELISA Kit - MBS733957 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Search more