UROS

Gene Symbol	UROS
Entrez Gene	7390
Alt Symbol	UROIIIS
Species	Human
Gene Type	protein-coding
Description	uroporphyrinogen III synthase
Other Description	hydroxymethylbilane hydrolyase|uroporphyrinogen-III cosynthase|uroporphyrinogen-III synthase
Swissprots	B2RC13 Q9H2T1 P10746 D3DRF7
Accessions	EAW49221 EAW49222 EAW49223 EAW49224 EAW49225 EAW49226 EAW49227 EAW49228 EAW49229 P10746 AF230665 AAG36795 AK314896 BAG37410 BC002573 AAH02573 BC004338 AAH04338 DQ891936 ABM82862 DQ895123 ABM86049 DR156879 J03824 AAA60273 XM_005270137 XP_005270194 XM_005270138 XP_005270195 XM_005270139 XP_005270196 XM_005270140 XP_005270197 XM_005270141 XP_005270198 XM_006717960 XP_006718023 XM_011540126 XP_011538428 XM_011540127 XP_011538429 XR_246103 XR_945809 XR_945810 NM_000375 NP_000366
Function	Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:11112350}.
Top Pathways	Porphyrin and chlorophyll metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-UROS-cDNA-Clone - DC01012 from Abgent, a WuXi AppTec company Prices $357.75 Sizes 10 µg Species Human Accession BC002573

UROS - MBS1275858 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC002573

human UROS ORF clone - CDCH098488 from Creative Biomart Species Human Accession NM_000375

human UROS ORF clone - CDCH098489 from Creative Biomart Species Human Accession NM_000375

Human UROS Gene ORF cDNA clone in cloning vector - HG14342-G from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14342-ANG from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14342-ACG from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid, N-HA tag - HG14342-NY from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid, C-His tag - HG14342-CH from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid - HG14342-UT from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid, C-HA tag - HG14342-CY from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14342-NF from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14342-NM from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14342-CF from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14342-ACR from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14342-ANR from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14342-CM from Sino Biological Species Human

Human UROS Gene ORF cDNA clone expression plasmid, N-His tag - HG14342-NH from Sino Biological Species Human

Human UROS ORF Clone (BC002573) - CDCS405621 from Creative biogene Species Human Accession P10746

Human UROS ORF clone (BC002573) - CDCB159161 from Creative biogene Species Human

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