COL1A1

Gene Symbol COL1A1
Entrez Gene 1277
Alt Symbol EDSC, OI1, OI2, OI3, OI4
Species Human
Gene Type protein-coding
Description collagen, type I, alpha 1
Other Description alpha-1 type I collagen|collagen alpha 1 chain type I|collagen alpha-1(I) chain|collagen alpha-1(I) chain preproprotein|collagen of skin, tendon and bone, alpha-1 chain|pro-alpha-1 collagen type 1
Swissprots Q7KZ34 Q13903 Q13902 Q59F64 Q8N473 Q16050 Q15201 Q14992 Q13896 Q14037 Q15176 Q9UML6 Q9UMM7 Q7KZ30 Q8IVI5 P78441 O76045 P02452
Accessions AAA51847 AAA51992 AAA51993 AAA52036 AAA52052 AAA75386 AAB26324 AAB59363 AAB59373 AAB94054 AAD32608 AGO43920 CAA25082 CAA25394 CCO13712 CDL93516 CDM55394 CDM55575 EAW94630 EAW94631 P02452 AB209597 BAD92834 AK297731 BAH12658 BC036531 AAH36531 DQ590066 DQ893571 ABM84497 EU176569 ABW03370 J00110 AAA52289 J00111 AAA52290 J00112 AAA52291 J00113 AAN86574 JQ236861 AFD28984 K01228 AAA51995 M32798 AAA52049 M36546 AAA60150 S64596 AAB27856 S64717 AAB27677 S67495 AAB20350 X06269 CAA29605 X07884 CAA30731 Z74615 CAA98968 XM_005257058 XP_005257115 XM_005257059 XP_005257116 XM_011524341 XP_011522643 NM_000088 NP_000079
Function Type I collagen is a member of group I collagen (fibrillar forming collagen).
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}.
Tissue Specificity Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.
Top Pathways Focal adhesion, ECM-receptor interaction, Amoebiasis, Protein digestion and absorption, PI3K-Akt signaling pathway

Collagen I peptide - ab198239 from Abcam

Category Peptide
Prices $181.00
Sizes 100 µg

Cow Collagen I full length protein - ab7526 from Abcam

Category Protein
Prices $356.00
Sizes 500 µg
Source Native
Species Bovine
ab7526 used to generate a standard curve for ELISA, diluted to a concentration of 4, 2, 1 and 0.5 ug. Samples were from bovine LD muscle. ab34710 was used at a 1/1000 dilution as the primary antibody. See Abreview

Cow Collagen I full length protein - ab64010 from Abcam

Category Protein
Source Native
Species Bovine

Cow Collagen I full length protein - ab123462 from Abcam

Category Protein
Prices $522.00
Sizes 1 mg
Source Mammalian
Species Bovine

Cow Collagen I full length protein - ab123833 from Abcam

Category Protein
Prices $285.00
Sizes 5 mg
Source Native
Species Bovine

Human Collagen I full length protein - ab134516 from Abcam

Category Protein
Source Native
Species Human
SDS PAGE analysis of ab134516.

Human Collagen I full length protein - ab7533 from Abcam

Category Protein
Source Native
Species Human

Human Collagen I peptide - ab101220 from Abcam

Category Peptide

Human Collagen I peptide - ab104423 from Abcam

Category Peptide

Human PICP protein fragment - ab158152 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158152 on a 12.5% SDS-PAGE stained with Coomassie Blue.

COL1A1 / Collagen I Alpha 1 Antibody Blocking Peptide - LS-E3319 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

COL1A1 / Collagen I Alpha 1 Antibody Blocking Peptide - LS-E21971 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

COL1A1 / Collagen I Alpha 1 Antibody Blocking Peptide - LS-E21972 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Collagen I alpha 1 Protein - H00001277-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Collagen I alpha 1 Full length Protein - NBP1-97266 from Novus Biologicals

Category Protein
Prices $299.00
Sizes 500 µg
Species Human
Western Blot: Collagen I alpha 1 Protein [NBP1-97266] - Lane 1: Human Collagen Type 1. Lane 2: None. Load: 50 ng per lane. Primary antibody: Collagen Type I antibody at 1:1,000 overnight at 4C. Secondary antibody: DyLight 649 rabbit secondary antibody at 1:20,000 for 30 min at RT. Block: MB-070 for 30 min at RT. Predicted/Observed size: 139 & 130 kDa, 139 & 130 kDa for Collagen Type I. Other Band(s): Collagen Type I splice variants and isoforms.

Human Like Collagen Protein - NBP1-99527 from Novus Biologicals

Category Protein
Prices $329.00
Sizes 10 mg
Species Human

Collagen I alpha 1 Protein - NBP2-34217 from Novus Biologicals

Category Protein
Prices $389.00
Sizes 500 µg

Collagen I alpha 1 Protein - P4915 from Novus Biologicals

Category Protein
Prices $1,559.00
Sizes 1 mg
Species Human

COL1A1-Antibody-C-term-Blocking-Peptide - BP14490b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human Pro-Collagen I alpha 1/COL1A1, CF - 6220-CL-020 from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived, Gln23-Lys277 + Gly1094-Leu1464, with an N-terminal human CD33 signal sequence and 6-His tag.

Human Collagen Type I Protein (OPMA04189) - OPMA04189 from Aviva Systems Biology

Category Protein
Prices $480.00
Sizes 500 µg
Source Placental villi
Species Human

COL1A1 Blocking Peptide - 33R-3394 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

Collagen type I - RA001 from Acris Antibodies

Category Protein
Prices $340.00
Sizes 500 µg
Source Placenta
Species Human

Collagen type I alpha 1 chain - H00001277-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Collagen type I alpha 1 chain - H00001277-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human
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